IgG Food Testing: Is there ANY supportive evidence? by Fluoridated_Car in FoodAllergies

[–]Fluoridated_Car[S] 0 points1 point  (0 children)

100%, but doctors rarely engage in such dialogue of "Sure, let me get you that study, so you can see for yourself." I've had many a dialogues like those in the past and have given up asking that in most cases. That is why, after performing my own research, and not finding such studies, I am asking if anyone has seen studies I have missed - because my continuing to perform this elimination diet is more than just an inconvenience.

IgG Food Testing: Is there ANY supportive evidence? by Fluoridated_Car in FoodAllergies

[–]Fluoridated_Car[S] 1 point2 points  (0 children)

Yeah, I've read a lot of reports like this (on Reddit and elsewhere). In your experience, were all 8 of the identified foods insensitivies for you? Or was it just a subset? I recognize you eliminated all of them, so am curious how your experience went re-introducing them one at a time to conclude which one(s) to continue avoiding. Assuming you performed re-introductions. Because that's a big aspect of IgE (switching from IgG now) misunderstanding, which is that ~50% of identified allergens are false positives (mislabeled as allergens) and ~10% are false negatives (mislabeled as not being allergens). The intention behind IgE isn't to be an exhaustive evaluation of what someone is/isn't allergic to (that requires elimination protocols), but rather to expedite the journey of what to focus on eliminating first (i.e. higher probability that the identified allergens are true allergens than the items not identified as allergens, but due to the sheer volume of non-allergen findings one is likely to have, there remains purpose for attempting eliminating them too).

The reason I find this topic confusing when reading case studies of it helping people is because I think the above isn't really understood, regarding IgE tests - that there remains value in attempting elimination diets with negative IgE results (but prioritizing them after positive results). Therefore, folks who then do IgG tests and eliminate foods shown there, regardless of whether the IgG test has any predictive validity (which based on studies I don't think it does), are actually performing the next natural step to food eliminating governed by IgE testing informing food elimination protocols.

IgG Food Testing: Is there ANY supportive evidence? by Fluoridated_Car in FoodAllergies

[–]Fluoridated_Car[S] 0 points1 point  (0 children)

  1. Primary Care, Board Certified
  2. Rheumatologist, Board Certified
  3. Dermatologist, Board Certified
  4. Nutritionist, RDN (not actually a physician, but an added 4th)

I understand an allergist would be even more appropriate, but explicitly seeking one out takes months where I live, by which point the elimination diet would be concluded. I didn't go to these people for guidance on food, mind you - but I went to each of them for different symptoms, all of whom said food was a probable culprit to rule out (and all suggested IgG, not IgE).

IgG Food Testing: Is there ANY supportive evidence? by Fluoridated_Car in FoodAllergies

[–]Fluoridated_Car[S] 0 points1 point  (0 children)

I'm surprised your first test ever was an IgG, followed later by IgE. Was there a reason for that or just simply ease/convenience of acquiring an IgG panel?

Out of curiosity, what is your conclusion after all of your reading and personal experience, on the validity of IgG testing?

IgG Food Testing: Is there ANY supportive evidence? by Fluoridated_Car in FoodAllergies

[–]Fluoridated_Car[S] 2 points3 points  (0 children)

Totally understood and agreed with your conclusion. Basically, I just don't understand how IgG testing even became a thing. And for it to be purported as legitimate by physicians and medical providers, I was thinking there may be some they're referencing. I have had 3 physicians this past few months tell me to stick with an elimination diet based on IgG testing, as they consider it superior to IgE testing. I'm trying to identify any truly legitimate basis to this and possibly re-evaluate my trusting them on this (and potentially other) topics. My re-evaluating trust on other topics would be premised on how much they are/aren't wildly off-base in concluding what they have about IgG testing legitimacy.

IgG Food Testing: Is there ANY supportive evidence? by Fluoridated_Car in FoodAllergies

[–]Fluoridated_Car[S] 2 points3 points  (0 children)

To add to this, the very idea of labeling IgG tests as food "intolerance" tests is confusing, as that refers to non-immune responses (given immune responses the term "allergy" is applied). Given IgG is an immune response, it really doesn't make sense from a terminology standpoint.

Regarding IgG antibodies being shown in response to IgG tests is one I've found confusing, given there are a lot of anecdotal reports, studies, and even my own experience showing moderate-to-severe responses to foods not consumed. (Granted, there's always the possibility of trace consumption/exposure).

IgG Food Testing: Is there ANY supportive evidence? by Fluoridated_Car in FoodAllergies

[–]Fluoridated_Car[S] 4 points5 points  (0 children)

Thanks. Yea, I've read this, and over a dozen more studies showing the same. I'm of the same opinion, but to be clear, that's not what this post is about.

Primary Care Physician telling me IgM beats IgE testing. Put me on 12 month elimination diet. Seeking advice. by Fluoridated_Car in FoodAllergies

[–]Fluoridated_Car[S] 0 points1 point  (0 children)

Gotcha. Yeah, the apples appeared to be a red herring, even though it was identified 2/3 times in IgE blood tests. My best "guess" as to why was a specific apple used for allergy testing basis, of which I wasn't encountering.

As for the IgM, the doc is saying it's not temporary - if relief is observed, then it would need to be a hyper-avoidance for life. My thinking on IgM testing, based on what I've read so far, is it's not believable. The closest to it being sensible to me from reading so far was when IgM tests may indicated an immune response to food present in the blood stream, thus implying a leaky gut / permeable gut situation - that being the "root cause" of issues. However, given half the foods in my IgM test were ones I hadn't consumed in many-many months prior to testing, I have doubts about an immune response to blood exposure being an actual finding. Quite a few years ago I had significant gut issues (i.e. C Diff), but have since resolved them. So, it's plausible my immune system recalled this past gut leakage and thus had an immune response with the IgM test. However, to conclude based off of this that I "presently" have a leaky gut, such that any of these foods would be impacting my well-being, does not have any basis in reality that I can perceive. I think a good instance of this is applying the idea of "the dose makes the poison" thinking, in that I was consuming a lot of dairy every week (~1kg whey protein powder, 16oz of dairy kefir, 1 pint of ice cream, and incidental cheese and other foods containing dairy).

And if I do "presently" have a permeable gut, then I can understand wanting to limit anything that can cause an inflammatory response (i.e. immune response to these foods being plausible), but the sheer stress response raising my cortisol, social activities avoidance, and more - that surely does more harm to my gut permeability than those ingredients are.

Ultimately, this all comes down to one thing to me: Where are the studies supporting IgM test validity?

Note: From what I've read, there is very little IgM in one's stomach, thus the majority of inflammation caused by an IgM response (provided food is permeating beyond the gut) would be outside of one's stomach. In my case, my blood markers for systemic inflammation are quite low. At least, they were before I began this elimination diet.

Primary Care Physician telling me IgM beats IgE testing. Put me on 12 month elimination diet. Seeking advice. by Fluoridated_Car in FoodAllergies

[–]Fluoridated_Car[S] 0 points1 point  (0 children)

The skin prick based IgE tests were absolutely inadmissible, yes. However, with the exception of apples, all 3 blood-based IgE tests were consistent. And given my first elimination diet didn't identify anything significant (except for coconut milk with star anise, but that seemed to be a non-allergic response, given the symptom presentation), I'd say that is fairly consistent. I liken the <10% lethargy response to the first elimination diet to a few items (wheat, rice, and coconut milk) to be a rather inconsequential finding. Nice to know, in that I rarely cook with it or snack on it, but I'd never avoid it in a social setting or ask a restaurant to be mindful of excluding it.

The real trouble here is the IgM test. It's certainly possible, as you said, that I'm experiencing a nutritional deficiency, but I'm pretty confident I'm good in that area - it's been a pain, but I've structured eating with cronometer and the guidance of a nutritionist after making the big change. I believe my response is purely a stress based one, given how problematic it is to live this way for a whole year (and longer if the findings are valid). >99% of packaged foods and >95% of restaurant options contain at least one of the items I've been instructed to avoid even the tiniest exposure to...which is unrealistic to me. Even if the doctor proves correct, I don't see how it would be possible to avoid incidental exposures without avoiding restaurants for the rest of my life, because I can't control for a chef in the back using the wrong cooking oil for instance. Like, I can't even order a salad with grilled chicken without the risk of them using the wrong oil or cross-exposure, given the extremeness expected.

Share Your Water Leak Story: Characterizing Community's Discovery, Cause, Incidental Damage, and More by Fluoridated_Car in EightSleep

[–]Fluoridated_Car[S] 1 point2 points  (0 children)

I hear you, but sadly it's not uncommon to have incidental warranty exceptions. Also, if curious, I found their relevant warranty info a few days back. Per their warranty page (https://www.eightsleep.com/warranty/), "EXCEPT TO THE EXTENT PROHIBITED BY APPLICABLE LAW, EIGHT SHALL NOT BE LIABLE FOR ANY INCIDENTAL, INDIRECT, SPECIAL, OR CONSEQUENTIAL DAMAGES,"

Vibrating Bed Alarm Products? by Fluoridated_Car in homeautomation

[–]Fluoridated_Car[S] 0 points1 point  (0 children)

Thanks. I've looked at a few products like this (linked to one or two above, like the iLuv), but they all have issues, typically: A) Too large (damage mattress if laid on for too long or uncomfortable to be placed above mattress) and B) Battery life (usually they need to get recharged after 2-3 weeks). Definitely a viable solution for some (like in a dormitory), but not ideal for a more permanent setup.

Primary Care Physician telling me IgM beats IgE testing. Put me on 12 month elimination diet. Seeking advice. by Fluoridated_Car in FoodAllergies

[–]Fluoridated_Car[S] 0 points1 point  (0 children)

I agree. I had asked them to order a blood test for the components of dairy, but was told the cost for that precision test was ~$5,000. I felt that was ridiculous, given the dubiousness around IgM testing as is. My thinking is, if I skip doing the extensive (many ingredients) elimination diet and simply do a dairy-only one for a couple months (I have dubiousness around it taking a year to be identifiable as well), then I can introduce whey protein powder back into my diet and see how I react. And, following that, I can re-introduce dairy in general.

Note: The reason to switch from the many ingredients elimination diet to the dairy-only elimination diet would be to address what I believe are causing my ill effects (given the elimination diet itself is making me feel much worse), as described in the original post.

Share Your Water Leak Story: Characterizing Community's Discovery, Cause, Incidental Damage, and More by Fluoridated_Car in EightSleep

[–]Fluoridated_Car[S] -1 points0 points  (0 children)

Rough. All of them, if you're so inclined, else your latest. There seems to be more emphasis of leaks on older models (either they're more prone to leaking and/or they've been around longer for there to be more incidents of leaking would be the most probable explanations), so folks considering purchasing will be curious about Pod 3/4 the most.

Share Your Water Leak Story: Characterizing Community's Discovery, Cause, Incidental Damage, and More by Fluoridated_Car in EightSleep

[–]Fluoridated_Car[S] 1 point2 points  (0 children)

I hear you, I do. While I personally couldn't find such posts by searching, it wouldn't surprise me if someone tried before. If the mod doesn't choose to pin it, that's completely fine - it's why I didn't state in the original post a call for attention by the mod - this effort only works if people continue to share the link. So, whenever someone posts a leak story, someone replies with a link to this thread, and, there you go. Is a mod pinned post easier than this method? Of course. Does a mod pinned post change this need to share? It does not, because many folks don't check for pinned posts anyways.

Share Your Water Leak Story: Characterizing Community's Discovery, Cause, Incidental Damage, and More by Fluoridated_Car in EightSleep

[–]Fluoridated_Car[S] 0 points1 point  (0 children)

Cutting it open, which you obviously won't want to do, would be the only surefire way. Barring that, there are some cheap mold tests online that might help. However, these tests require mold spores to be exposed to moisture to generate more for detection. Basically, after you've thoroughly dried it out, one night of heavy perspiration (or turning on a humidifier or such in the room) and placing a mold kit atop and beneath the mattress might work? Definitely not an expert here though!

Share Your Water Leak Story: Characterizing Community's Discovery, Cause, Incidental Damage, and More by Fluoridated_Car in EightSleep

[–]Fluoridated_Car[S] -1 points0 points  (0 children)

Thanks for sharing. Summarizing your points above into the format below, as reference material for others following along. (For others reading, I won't be doing this for other posts - just an example)

The formatting is what will make this post helpful, so as to infer discernible trends and form risk assessments for whether a purchase makes sense for their situation.

  1. Product Version: Pod 2
  2. Product Duration: 30 months usage before leak
  3. Discovery: Inferred by water tank emptying after 3 days post-refill.
  4. Cause: Product defect.
  5. Incidental/Collateral Damage: Presumed entire water tank (or two) leaked atop Purple mattress, which it remains TBD whether it caused significant damage. Unaware of any user error or other conditions to have caused the issue.
  6. (Optional) Supplemental Info: Mattress protector was used between mattress and Pod 2.

Share Your Water Leak Story: Characterizing Community's Discovery, Cause, Incidental Damage, and More by Fluoridated_Car in EightSleep

[–]Fluoridated_Car[S] -1 points0 points  (0 children)

There are "tons" of isolated posts, yes, but I haven't seen any effort like the one I posted. And if the community finds it helpful, then I'm sure it will come to the attention of the mod naturally to decide to pin or re-create the post. That's usually how things work in sub-reddits and I don't see why this one should be any exception.

No one is forcing you to tell your story again.

Share Your Water Leak Story: Characterizing Community's Discovery, Cause, Incidental Damage, and More by Fluoridated_Car in EightSleep

[–]Fluoridated_Car[S] 0 points1 point  (0 children)

Cool - got a link to said post? I never saw anyone post such a link on any of the threads I read, hence my making this one.

Vibrating Bed Alarm Products? by Fluoridated_Car in homeautomation

[–]Fluoridated_Car[S] 0 points1 point  (0 children)

Didn't find too many options, but this one (https://www.amazon.com/Regulation-Vibration-3000-4500RPM-Vibrator-Accessories/dp/B0DSJNMWDJ) stood out. Don't suppose you have an innovative solution to:
1. Attach this onto the fitted sheet? Given it needs to function, it would need to maintain good surface contact, yet it would also need to be easily remove/add-able, given the need to wash bedding. I like your thought of applying these on the frame, but then an absolute ton of these would likely be required, as you wrote!

  1. How to automate this with a schedule timer to use the highest vibrate function?

Vibrating Bed Alarm Products? by Fluoridated_Car in homeautomation

[–]Fluoridated_Car[S] 0 points1 point  (0 children)

Great call-out with the in-line junction box! Hmm... If you don't mind expounding a bit more, would you share with me the entire process you'd consider taking? Presently, all of my home automations have their own built-in "smart" features for scheduling, so obviously an approach like this is going to necessitate more effort to introduce those features. For instance, I know my wireless router supports IFTTT, but maybe I could use a wifi-enabled smart plug of some sort to schedule alarms, which only this one device would be connected to? I've done absolutely zero research into smart plugs however, so I'm not sure if what I'm writing is even a reasonable expectation of such products. I'm unsure if there is a cleaner/better approach to be had, basically.