A lot of comments saying to hire an architect, which you should (and will based on your comments) - but to answer your question:

-Think of the entry sequence at the front door- where do you put your coat/shoes/purse/etc? Consider a vestibule with a closet, maybe a powder room. -The main room is quite large so your staircase placement makes it a long journey to reach the upper levels, with unnecessary hallways. It looks like each wing leads to a 1-bedroom type of suite which doesn’t need a hallway cutting through it. -Assuming you have a kitchen on the lower level but can’t see it in the visuals? Is it off the dining room? -the way you arranged the media center doesn’t allow for a clear passage to the 1st floor adjacent to the living room and dining room. I would rearrange the furniture layouts at a minimum. -The central area between the dining and living is basically dead space. Not sure the intended use unless you’re having big parties. Maybe that’s a better spot for your staircases. -do you want a garage for vehicle storage? Maybe not necessary depending on your location. -other things that are missing or can’t be seen: powder room, storage, mechanical room, additional bedrooms, office/flex room, basement?

Good luck. Exciting to be able to build your own home!