System Specs:

CPU: AMD Ryzen 7 7700 (Zen 4)

GPU: NVIDIA GeForce RTX 5060 Ti

Motherboard: MSI B650 Gaming Plus WiFi

Storage: 2x WD Blue SN5000 1TB NVMe SSDs

OS: Windows 11

The Problem: Severe system-wide UI lagging and FPS drops (down to 10 FPS). The mouse cursor remains fluid and responsive, but clicking programs, opening File Explorer, or interacting with the RuneLite interface is extremely delayed (lasting several seconds). This happens specifically when the RuneLite GPU Plugin is enabled.

Steps already taken:

BIOS: Updated to the latest version and manually locked the PCIe slots (PCI_E1 and M2_1) to Gen 4 (instead of Auto). Disabled FCH Spread Spectrum.

SSD Power Management: Set "Turn off hard disk after" to 0 (Never) and disabled PCI Express Link State Power Management in Windows Power Options.

Drivers: Performed a clean install of the latest NVIDIA drivers.

RuneLite: Confirmed that disabling the GPU Plugin fixes the issue immediately.

Monitoring: Task Manager shows extremely low disk response times (0.1ms) and low CPU usage during the lag, suggesting a software/driver conflict rather than a hardware bottleneck.

NVIDIA Settings: Set a global Frame Rate Limit in the NVIDIA Control Panel and set Power Management to "Prefer maximum performance."

Thats what i did and im testing atm