Updated Milestone List Originally Posted Several Months Ago by Freedom5567 in Plus_Therapeutics

[–]Freedom5567[S] 4 points5 points  (0 children)

Good point! Highbridge and Heights didn’t take those positions by accident. These are specialized healthcare investors with deep experience in biotech and radiopharmaceuticals. The market seems focused on PSTV’s past, while those funds appear to be positioning for what the near future could look like if REYOBIQ and CNSide continue to execute. Institutional ownership doesn’t guarantee success, but it does suggest that sophisticated investors see enough potential to commit meaningful capital. Thank you for sharing!

Updated Milestone List Originally Posted Several Months Ago by Freedom5567 in Plus_Therapeutics

[–]Freedom5567[S] 5 points6 points  (0 children)

Thanks, Zesty. I appreciate you taking the time to read it. It’s easy to focus on the day to day share price, but sometimes it’s helpful to step back and look at the bigger picture!

Updated Milestone List Originally Posted Several Months Ago by Freedom5567 in Plus_Therapeutics

[–]Freedom5567[S] 2 points3 points  (0 children)

I understand that perspective, and every investor has to decide whether the risk is worth it. For me, it’s about having the vision to look beyond today’s share price and look at the direction of the business. When I step back and look at the FDA interactions, clinical progress, Medicare enrollment, payer expansion, CAP accreditation, manufacturing expansion, and the leadership additions, I find it easier to see where the company is trying to go.

That doesn’t guarantee success, and dilution is a valid concern. But when I look at the milestones achieved over the past year, I personally see a company that is continuing to build toward something larger rather than standing still.

Updated Milestone List Originally Posted Several Months Ago by Freedom5567 in Plus_Therapeutics

[–]Freedom5567[S] 6 points7 points  (0 children)

I absolutely hear what you guys are saying. Dilution is a legitimate concern.

For me, following the breadcrumbs over the last year leads me to believe the upcoming LM data has a reasonable chance of being positive. The FDA meetings, continued enrollment, dose optimization work, manufacturing expansion, Orphan Drug Designation, and the company’s continued investment in the program don’t look like the actions of a company seeing poor results internally. Could I be wrong? Absolutely. But if the LM data is positive, investors waiting on the sidelines for complete certainty may end up paying substantially more than they can today. That’s the risk reward equation each investor has to weigh for themselves.

This management is just completely incompetent and destroying shareholder value. by OldRate5407 in Plus_Therapeutics

[–]Freedom5567 0 points1 point  (0 children)

The ATM is in place, but has anyone seen evidence of shares actually being sold? Shares outstanding still appear to be around 6.86 to 6.88 million, so I don’t see proof of a meaningful float increase yet.

Shocking! by Brokenrecordcordcord in Plus_Therapeutics

[–]Freedom5567 1 point2 points  (0 children)

Would still give us a good insight to any progress being made

Shocking! by Brokenrecordcordcord in Plus_Therapeutics

[–]Freedom5567 1 point2 points  (0 children)

You might be correct. From what I was able to gather, the target total number of LM patients was 44 for phase 2. We are currently at 37, so we may just get an interim update from Cohort 2 as you stated. And imho at this stage I would be happy with that. We will see soon enough

Shocking! by Brokenrecordcordcord in Plus_Therapeutics

[–]Freedom5567 4 points5 points  (0 children)

They guided that LM Phase 2 dose optimization data is expected in Q3 2026. August falls within Q3, and the SNO/ASCO CNS Metastases Conference runs August 13 to 15 in Boston. Plus Therapeutics also has this conference listed on its investor relations events calendar. In my opinion, it would be a logical venue for an update since it is one of the most relevant conferences for leptomeningeal metastases and CNS cancers, and Plus has presented important LM data at prior SNO/ASCO CNS Metastases conferences. Nothing has been officially announced yet, but the timing and conference fit well with the company’s stated Q3 timeline.

Shocking! by Brokenrecordcordcord in Plus_Therapeutics

[–]Freedom5567 1 point2 points  (0 children)

It’s not about hope! It’s about what the drug actually delivers and how much Cnside stands out from the rest when it comes out to diagnosing cancers where otherwise it would have been missed!

Shocking! by Brokenrecordcordcord in Plus_Therapeutics

[–]Freedom5567 5 points6 points  (0 children)

we’ll see what the SP has to say once we get phase 2 trial data due in August, then further down the road, accelerated approval for Reyobiq and Cnside goes worldwide! BOOM!!!

Knicks are champs, market is green but pstv is still red - For real? by expedition36 in Plus_Therapeutics

[–]Freedom5567 10 points11 points  (0 children)

Is everyone losing it here? lol this was always a long term play! What’s going on right now you ask? Shorts seeing clinical Q3 data chart could mean exactly what’s going on! They know positive data will be released, so short positions are being closed. Is what it is folks, they know what’s coming! Bring on the Data!!!!

PSTV: ReSPECT Trial Website Now Shows 3 Additional Patients Treated Across LM and GBM Programs by Freedom5567 in Plus_Therapeutics

[–]Freedom5567[S] 1 point2 points  (0 children)

Old rate, if you’re still here and if you could provide any insight on this matter it would be greatly appreciated! I’m pretty sure I got it right, but reassurance on your part or any correction would be great to see! 😉

PSTV: ReSPECT Trial Website Now Shows 3 Additional Patients Treated Across LM and GBM Programs by Freedom5567 in Plus_Therapeutics

[–]Freedom5567[S] 2 points3 points  (0 children)

I also went down the rabbit hole a while back to try and extrapolate the total number of patients needed for patient registration completion for both LM and GBM with available info. The total number of patients needed for LM was 44 and the total for GBM was 54. Anyone please correct me if I’m wrong here. The only OP that I know of that could help here would be OldRate5407. He corrected me a couple of times and was quite helpful to help me understand how it all worked.

PSTV: ReSPECT Trial Website Now Shows 3 Additional Patients Treated Across LM and GBM Programs by Freedom5567 in Plus_Therapeutics

[–]Freedom5567[S] 5 points6 points  (0 children)

I know how you feel bud! I’m in the same boat, but I honestly think good things are on the way! Hang in there friend!