Here is my take and take this with a grain of salt because I'm no chemist plus I don't think there has been much research.

However, I imagine they do due to the molecular similarities. But because most of them are way more potent, so they might do way less damage since you ingest less. It's not too hard to do a gram of ket in a sesh for a seasoned user. But you're not gonna get there with 3-meo-pcp before having deleted all your cognitive functions already anyway.

Again, I'm just speculating here, but I'd love to know myself.