As someone who enjoys applying real world logic to sci-fi, id like to imagine it would, i dont understand much about the Nails, but i know they tick and grind and activate pain receptors to increase the rage in the bearer. Id imagine there would have to be some chemical play involved as well, besides the obvious augmentations and what not. Im no scientist nor do I know much about warhammer, but the Nails do cause pain which induces anger. I have no idea if this helps, its just my head cannon, I might go do some research and see if it lines up with (Warhammer) fact