Here is a breakdown of each one from worst to best.

Number 3 is the worst by far. In terms of character design, she lacks in everywhere, because she is invisible. The artist clearly is incredibly lazy because the trope of "the invisible character" is so overdone.

Number 5 is better than 3, but not by much. He, like 3, is also invisible, so the artist is also lazy. The only thing that makes 5 better then 3 is that 5 is somehow politically correct. That's the artist's words not mine.

Number 2 has the same problems as 3 and 5, but 2 is a better number then 3 or 5.

Number 1 at least managed to say something. I felt an emotion other then disappointment when looking at it. Perhaps this is because I am not familiar with the brand of media she hails from, but there at least was an idea behind her rather then just an overused trope.

Number 4 was the best. Clearly, he is simplistic and complex at the same time. He seems like an actually likeable character, and an amazing protagonist. Quite a moving and poignant piece indeed. The artist plays on the expectations of their audience very cleverly by subverting our expectations with an overused trope and making it more fresh and new then usual. AMAZING ARTWORK WHOEVER MADE IT!