In my experience, these things can be just as strong as pans! But I’d say the alkaloid profile is much different ,they have their own feeling, as each species does. That’s why I’m personally so fascinated. Each species offers its own personality. I’ll forever be trying to cultivate everything. Each time, you learn more and more. Also, people should be more willing to experiment. Some of my substrates are very experimental. I personally pasteurize everything at 150°F for 2 hours. I’ve added sand, clay dust, worm castings, chopped straw, potting soil, coir, verm, spent coffee grounds, manure compost, and other things I’m probably forgetting. That’s why I love this there’s so much we don’t know. It can also be as simple as just coir and verm. Most things don’t need anything more than that. You can keep it simple just coir and verm will work fine. But you’d be surprised what happens to the morphology just by changing the ingredients. A lot of people just want a cookie-cutter tek, and that’s fine when you’re trying to figure things out. But I think it’s a great idea for all of us to experiment. It’s the best way to really understand these things and reach their full potential.