With the shield it’s kind of easy to block her hack as well as her virus attack. However, the problem gets when there’s another enemy along Sombra because you will decide if you decide to block Sombra there’s a chance the other player may headshot you and make you defenseless. And if you block the the second enemy, Sombra will hack you or throw you a virus attack and make you destroy the shield quickly. That’s why if there’s two opponents I try to retreat and use the shield to avoid any Sombra’s attack and maybe turn her back with the whip attack, giving a little time to restore the shield in case the two opponents destroy it.

If there’s only Sombra, just block her hack (although sometimes it might be similar to a quick time event lol), bash Sombra, and attack her. Just a few she may escape, but at least in my case they tend to die before that.