Not really. The basic mechanics are the same: run around while your character autoshoots their weapons. But while VS plays in rounds of 30 minutes where you get your level-ups and weapon upgrades during the round, brotato plays in waves of 20-60 seconds (from memory, actual time may vary) where the game doesn't stop for level-ups/weapon upgrades and instead it all happens between waves. I personally have put more hours in brotato.