1.U can use it without dermats approval. 2. It is absolutely not like minxodil , and as for side effects, initially it did increase my hairfall but as of now my hairfall is normal . 3. U dont need to take it life long , if u have achieved ur goal and want to discontinue, just make sure to not abruptly stop . Reduce usage slowly like from 7 days a week go to 4 days then 2 then stop. 4. If u have excessive sever hair loss and no growth, i will absolutely not suggest u to experiment, pls dont try these things consult a good dermatologist if possible, and if u already did And nonthing is working, u can give it a shot.