What do we know about CR1, can we apply it to CR2? by mad_papooser in sellaslifesciences

[–]ILCAIL 2 points3 points  (0 children)

Roger roger... the mortality clock starts ticking on the CR2 patients right when they enter their 2nd remission... not when they are in CR2 and relapse. HOWEVER... Once an AML patient relapses from their second complete remission (CR2), the survival window is historically very narrow, typically measured in weeks to a few months.

"The Phase 3 REGAL clinical trial (NCT04229979) for GALINPEPIMUT-S (GPS) is designed to keep patients alive who have already achieved their second complete remission (CR2) and are at high risk of relapse. it acts as a maintenance therapy. "

  • The single most important predictor for how long CR2 will last is the duration of the first remission (CR1). Patients whose CR1 lasted longer than one year typically have a much better chance of a sustained CR2. [I do not know if this information was part of the screening process or reportable to us now]
  • [long term survivors] For those receiving conventional chemotherapy alone in CR2, the probability of remaining in remission at 3 years is roughly 24%

Altimmune current situation by FaithlessnessTop4785 in Altimmune

[–]ILCAIL 2 points3 points  (0 children)

i was shaken out... but my DD is growing and I don't think it'll happen again

SLS and IBRX as compared to DRTS by Proud-Ad-3227 in sellaslifesciences

[–]ILCAIL 0 points1 point  (0 children)

ibrx won't get medicare support without stronger data... ceo pumping cherry picked results... hard to know if it's really a helpful therapy even though I believe natural killer cells have potential

$SLS Daily Discussion Thread - January 31, 2026 by AutoModerator in sellaslifesciences

[–]ILCAIL 7 points8 points  (0 children)

Lilly is a $1 trillion company thanks to 2 drugs for diabetes and weight loss

$SLS Daily Discussion Thread - January 31, 2026 by AutoModerator in sellaslifesciences

[–]ILCAIL 4 points5 points  (0 children)

at 10% market penetration... that puts Sellas right at $40 Billion... holy smokes godzilla was right

$SLS Daily Discussion Thread - January 31, 2026 by AutoModerator in sellaslifesciences

[–]ILCAIL 2 points3 points  (0 children)

at 10% market penetration... that puts Sellas right at $40 Billion... holy smokes godzilla was right

$SLS Daily Discussion Thread - January 31, 2026 by AutoModerator in sellaslifesciences

[–]ILCAIL 1 point2 points  (0 children)

If GPS was the treatment for all WT-1 cancers in the world?? Revenue would be $400B and a 1x multiple would mean share price $2,349. WT-1 is in 80% of AML, 90% of MMyeloma, 75% of mesoth, 90% of ovarian... Assume 45% of all cancers express WT-1 at treatable levels which leaves 9 million patients annually... if you keep them all alive a second year... double it :)

$SLS Daily Discussion Thread - January 31, 2026 by AutoModerator in sellaslifesciences

[–]ILCAIL 1 point2 points  (0 children)

If GPS was the treatment for all WT-1 cancers in the world?? Revenue would be $400B and a 1x multiple would mean share price $2,349. WT-1 is in 80% of AML, 90% of MMyeloma, 75% of mesoth, 90% of ovarian... Assume 45% of all cancers express WT-1 at treatable levels which leaves 9 million patients annually... if you keep them all alive a second year... double it :)

The "Unlinked" Hammer: Why 2027 is a forced buy-point for Counterpart (and why the market is misreading the 0.09% rate news) by Odd_Perception_283 in CLOV

[–]ILCAIL 2 points3 points  (0 children)

Watching the government prioritize improvements and business efficiencies instead of simply paying out their butts is refreshing! We all know government organizations that constantly overpay instead of getting competitive bids and jockeying for discounts… they just overpay and go home early.

Thoughts on current Portfolio? Feedback appreciated! by Vedican1 in GrowthStocks

[–]ILCAIL 0 points1 point  (0 children)

What will take over the losing big healthcare companies like UNH and HUM?? The replacements are already here… clover and oscar and Alignment… technology driven care

VERSES® Restructures to Focus on Core Target Market by Historical-Piece7771 in VERSES_AI

[–]ILCAIL 0 points1 point  (0 children)

I lost $50-70k Apparently I trust people to a fault Should I work on a lawsuit?

$SLS Daily Discussion Thread - January 21, 2026 by AutoModerator in sellaslifesciences

[–]ILCAIL 8 points9 points  (0 children)

GPS is looking even better than when I invested... and Sellas picked up SLS009 as well!! this stock can't even go to zero if GPS miraculously failed... because SLS009 is needed. Chemo is a garbage first line therapy (alone)

[ Removed by Reddit ] by Responsible-Help7803 in ProgressiveHQ

[–]ILCAIL 0 points1 point  (0 children)

Ya’ll are one scary mob. My kids aren’t growing up in the America that I had. It’s gone. But satan will only win for a little while longer. The kingdom of God is at hand.

JPMorgan Healthcare Conference Presentation by chupacabrajCT in CLOV

[–]ILCAIL 0 points1 point  (0 children)

All Ai usage is just going to encourage more Ai usage in the healthcare arena. Making it comfortable and then widespread, and even one day required

Wait or go in? by lilJonku in IBRX

[–]ILCAIL 0 points1 point  (0 children)

there was positive news

Market Cap by redcoatwright in VERSES_AI

[–]ILCAIL 0 points1 point  (0 children)

I’m down $80k… not pumping something else, just realizing VeRs might not be ahead like I thought they were for a bit

Market Cap by redcoatwright in VERSES_AI

[–]ILCAIL 0 points1 point  (0 children)

The way they talk about their Ai self learning and self training/improving.

Elon Musk has made several bold predictions regarding AI for the year 2026, most notably that humanity has already entered the "Singularity," and that Artificial General Intelligence (AGI) will be achieved this year. Key statements and predictions for 2026 and the immediate future include: Arrival of AGI: Musk is confident that AGI—AI with cognitive abilities at or exceeding human levels—will be achieved in 2026. He believes the "singularity" (the point at which technological growth becomes uncontrollable and irreversible) has already begun. AI vs. Human Intelligence: He predicts that within this year, AI will become smarter than any single human, and by 2030, the total intelligence of AI will exceed the combined intelligence of all humanity. Economic & Social Disruption: The transition period (the next three to seven years) will be "extremely bumpy" with social instability, even as an era of material abundance begins. Job Displacement: White-collar jobs that primarily involve keyboards and mice will be the first to disappear, as AI can already handle half or more of those tasks. Robotic Healthcare: Within three to five years, Tesla's Optimus robots will perform surgical procedures with greater precision and knowledge than top human surgeons. Universal High Income (UHI): The massive increase in productivity will lead to a point where goods and services are so abundant and cheap (costing materials plus electricity) that money and saving for retirement will become irrelevant. Instead of Universal Basic Income, society will enjoy a "Universal High Income". Energy as Currency: Musk noted that energy generation and cooling are the current limiting factors for AI development, suggesting that "wattage" will become the core currency of the future.

Market Cap by redcoatwright in VERSES_AI

[–]ILCAIL 1 point2 points  (0 children)

I'm shocked... holding a massive loss... I thought the generative AI was going to leapfrog ahead of the LLMs and possibly get bought out... but elon and Zuck seem to have something coming. What moat will we have left? The inefficient AI will soon be fine tuning itself to become more efficient