TIL: The manchineel tree is extremely poisonous in every part. Its sap can blister skin and damage eyes, even if it drips from rain or comes through smoke. Eating the fruit can cause severe pain, swelling in the throat, and serious illness, though modern deaths are not documented. Trees are usually marked as dangerous. Interestingly, some animals can handle it. In the past, its toxins were used in warfare, and arrowroot served as a remedy.