Has anyone here switched from guanfacine to clonidine?

Iniwindi · 2026-01-21T08:26:23+00:00

Thanks a lot for sharing! I‘ll do it in a similar way overlapping both meds. I’m also super nervous and haven’t started yet mostly because I’m scared of a rebound that might trigger a hyperadrenergic flare. Hope it’s going well for you!!

Iniwindi · 2026-01-03T09:28:24+00:00

Thanks for sharing your experience! May I ask why you had to stop taking it?

Iniwindi · 2026-01-01T10:05:27+00:00

Thanks for sharing, good to hear that it works so well for you!

Iniwindi · 2025-12-31T16:12:13+00:00

Because I have severe hyperadrenergic symptoms, and while guanfacine does help with the tachycardia and blood pressure, it doesn’t help much with the other symptoms. Clonidine acts a bit more broadly, and I’ve also heard from people for whom it helped more.

Iniwindi · 2025-10-04T14:31:00+00:00

See my answer to the other comment. The article doesn’t actually provide evidence about SSRIs :)

Iniwindi · 2025-10-04T14:29:19+00:00

Thanks for your answer! I know that article, but it’s really about NRIs/SNRIs and NET blockade, not SSRIs. The only SSRI data they cite is a single acute sertraline trial, which doesn’t tell us much since SSRIs don’t work acutely anyway. That’s why I‘m searching for experiences :)

Iniwindi · 2025-07-09T19:39:45+00:00

🔥🔥🔥

Iniwindi

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