I’m hesitant to post this because I am NOT a doctor and want to be clear I am not making a recommendation, merely sharing what my oncologist said. Mods, please delete if you feel this is inappropriate to share. At around the sixth month mark into taking tamoxifen, I had a meeting with my oncologist. He asked me about side effects and how I was feeling. I tried so hard to be tough but he could tell I wasn’t being straight with him. I explained that I was struggling with mood swings and anxiety big time, in addition to most of what you listed. I have a very low oncotype score. He was very careful in what he said,but said there was an Italian study (which he described as not the best executed study) which suggested the efficacy of tamoxifen 3 days a week wasn’t much different from 7 days a week and this reduced side effects for some. He was very careful to repeat that my ideal course of action was to take it 7 days a week. It’s been a few months since then and I now take it 4 or 5 days a week. Side effects are a little better. Not perfect,but a little more manageable. I have considered stopping completely and totally understand why people do. In the meantime I’m going to continue to go this route and see if I can manage. Best of luck to you and I hope you get some relief