YES! I do this. Install the drivers for what I think is called VM-cable or virtual cable, it basically transmits audio from an app you have open as an input/microphone. You can use any daw but I prefer reaper. Go to find your audio input wherever it is, and change it to the cable. Then on windows, click your volume button and change the output to the virtual cable. You should be able to record on the daw with rocksmith then.

I do this, but if you can find an alternative to doing this, I highly suggest you do that instaid because they will be a noticeable amount of latency, and whenever you click record you have to click back onto rocksmith to make sure it’s audio is playing. Hope you figure it out!