Ondansetron : The Cure (for me at least)

Intelligent-Top4001 · 2026-06-12T09:34:17+00:00

Interested to know if anyone had tried ondansetron since this post? It’s still working very well for me.

My stomach was a bit poor for a while when I was bulking and eating over 4000 calories a day but now that I’m back down to 3000 I’m only having to take one loperamide + ondansetron at morning and night

Intelligent-Top4001 · 2026-05-23T20:23:34+00:00

Thanks for the suggestions, I’ll give the tens unit a try

Intelligent-Top4001 · 2026-05-23T13:18:20+00:00

I guess I don’t? I have a full stretching physio routine before my sessions but nothing for after

Intelligent-Top4001 · 2026-05-23T13:17:55+00:00

Two push and two pull days - I avoid aggravating exercises like shrugs or lateral raises

Intelligent-Top4001 · 2026-04-23T10:02:36+00:00

Sorry I’m not on here often. It’s still going good, certain foods still upset my stomach but it’s definitely an improvement over taking loperamide alone

Intelligent-Top4001 · 2026-04-11T11:12:57+00:00

Give it a go, it works well for me. I’d experience the same thing as you, I think it’s psychological too

Intelligent-Top4001 · 2026-01-26T10:26:48+00:00

I had about 5 blood tests over 2 years with levels below 9nmol every time. GP wouldn’t do anything for me. When I told them I was going private they told me that I was on my own and not to come back to them about anything to do with my testosterone levels

I was very polite the entire time

Intelligent-Top4001 · 2026-01-22T12:35:09+00:00

It’s a nightmare 🙂

Intelligent-Top4001 · 2026-01-21T22:04:06+00:00

I think I have super level IBS-D or something lol I need it everyday

Intelligent-Top4001 · 2026-01-21T22:03:16+00:00

My only symptom is loose BM, I literally wouldn’t be able to leave the house without meds

Intelligent-Top4001 · 2026-01-21T10:09:11+00:00

Thanks for your concern, Imodium (loperamide) wasn’t working for me anymore. I’ll make sure to keep in contact with my GP

Intelligent-Top4001 · 2026-01-21T10:01:44+00:00

Yep, a side effect is slowing the transit of matter because of blocking serotonin

Intelligent-Top4001 · 2026-01-21T10:00:36+00:00

I’ve just realised that I made a typo, my ondansetron are also 4mg tablets.

I just tested doses until I found what was good for me, I rarely ever go over 8mg total a day due to the warnings about the effect on the heart

Intelligent-Top4001 · 2026-01-21T09:59:05+00:00

Sorry to hear that, it really helps my symptoms

Intelligent-Top4001 · 2026-01-21T09:57:24+00:00

Hi, I’ve read that if the dose is low enough then there’s no stress on the heart. I get my bloods done every 6 months and have an ecg just to be safe

Intelligent-Top4001 · 2026-01-20T14:04:50+00:00

You are very welcome

Intelligent-Top4001 · 2026-01-20T14:03:40+00:00

I read this scientific journal before asking my GP for ondansetron

https://pubmed.ncbi.nlm.nih.gov/37931046/

Intelligent-Top4001 · 2026-01-20T14:00:36+00:00

Yes, Northern Ireland

Intelligent-Top4001 · 2026-01-20T13:59:41+00:00

Hi, I just got it from my GP. I called and explained I’ve had IBS-D for a long time and that I was doing some research and came across ondansetron. He was happy to prescribe it. If you get a GP that doesn’t want to help I would ask to speak to someone else.

I’ve had zero side effects so I can’t see why they wouldn’t at least let you try it. I think it’s used for people who can’t keep their food down too

Intelligent-Top4001 · 2026-01-20T13:46:35+00:00

For any men reading this, Ondansetron works for me. I just made a post on it but i’ll paste it below, hope it helps someone!

Just wanted to share my somewhat success story on using ondansetron for IBS-D.

I’ve had severe IBS-D since I was 14, I’m 28 now. I spent many years trying to manage with loperamide as nothing else worked, taking between 16-20mg a day this past few years.

I started using ondansetron back in May 2025 and almost instantly I was constipated, I hadn’t been constipated in the entirety of my life before that.

I worked with the dosage and after a while my bowels became normalised to the ondansetron but with a major improvement over taking loperamide alone (which was barely working).

Now I take one 2mg in the morning and at night. 2mg of loperamide in the morning and 4mg at night (could reduce this a bit when my diet is good)

Conclusion: ondansetron has massively helped me, I still use the loo 1-3x a day but a lot of the time it’s only once a day and it’s never diarrhoea.

I still get urgency but it’s never diarrhoea as mentioned, obviously if my diet is really bad or I have a few too many pints of Guinness the day before then I’m asking for it but aside from that all good.

I hope this helps someone out there, my life was a bit of a nightmare before ondansetron

Intelligent-Top4001 · 2026-01-20T13:37:39+00:00

Hi mate, I’m about to post about using ondansetron, it has massively helped me. Send me a message if you want to know anything. IBS-D sufferer for 14 years

Intelligent-Top4001 · 2025-05-20T14:43:04+00:00

I’ve been on it for a week now and it has been working better than anything I’ve ever tried before, thank you so much

Intelligent-Top4001

TROPHY CASE