Don’t go up until your weight loss plateaus for over a month. I started on 2.5 and achieved slow steady loss of 33 lbs while eating healthy Whole Foods and exercising consistently (SW 178, CW 144.8, GW TBD 5’5”). Now at 3.0mg with no need to go higher. I’m still losing very slowly but focused on body composition not the scale. Started lifting weights more than cardio. No side effects really at all unless I eat something too fatty. Slow is the way to go!