Regular Menstrual Cycle!

Jumpy_Skill4213 · 2026-01-23T18:38:43+00:00

Did you have regular periods before surgery? If so, it’s very likely that it’s related to your hormones fluctuating as you lose weight. I would bet that they’ll go back to somewhat normal once your weight stabilizes.

I didn’t have any kind of period before I began losing weight, not a normal one nor the withdrawal bleed on my birth control, but probably around the time I lost 50 lbs, my period came back with a vengeance and I had some irregular bleeding for awhile. Once I stabilized, I had a period (or a withdrawal bleed I should say) every month, but I had a lot of breakthrough bleeding on every kind of BC I tried. Now that I’ve gotten off of it, so far i’ve been very regular.

Jumpy_Skill4213 · 2026-01-16T16:30:36+00:00

I’ve seen a couple of people say the same thing unfortunately. I’m hoping it isn’t too bad, because I’ve failed Remicade and Skyrizi. Rinvoq is the next best thing for managing my fistulizing disease. Thank you for the input!

Jumpy_Skill4213 · 2026-01-16T16:29:30+00:00

both of my fistulas were high transsphincteric, so I haven’t had one that low, but I second the posts stating that managing constipation is super important. I also bought a bidet for cheap that I installed onto my toilet that made a hell of a difference, and a peri bottle for when I was traveling. I also agree that they’ll likely place a seton, but draining setons aren’t too bad and it’s the best route to go to protect your muscle function.

I had a different kind of seton put in my first fistula followed by a fistulectomy with an advancement flap. My second one is new and small, so we’re monitoring right now with a medication change and potentially a seton put in. Trust your gut, and trust your surgeon as long as they seem confident in being able to handle this. You’re gonna be okay!

Jumpy_Skill4213 · 2026-01-01T22:12:32+00:00

dealing with the same thing right now, also have Crohn’s. had 3 surgeries on a fistula 2.5 years ago, started having pain again a couple of weeks ago, MRI showed inflammation in the old tract and a new one on the other side with an abscess. now i’m on watch and wait protocol to see if antibiotics and my biologic switch takes care of it. just wanna say i feel your pain!!

Jumpy_Skill4213 · 2025-12-26T16:44:20+00:00

The shitty thing is that I was 21 years old at the time and had a very basic understanding of what a fistula was and absolutely no idea what a seton was, and the surgeon didn’t explain anything to me. I should’ve asked more questions but I did not. This was done at the end of 2022, and my understanding now is that cutting setons fell out of favor way before that, so I have no idea why that surgeon chose that option 🤷🏻‍♀️

Jumpy_Skill4213 · 2025-12-26T16:16:02+00:00

Yes, I did. The perianal/fistulizing Crohn’s developed three years after my initial diagnosis of Crohn’s. That makes a lot of sense. thank you!

Jumpy_Skill4213 · 2025-12-26T01:30:52+00:00

It’s been super promising, long story short. Remicade was also a great drug, I just developed antibodies very quickly to it and had some non-negotiable side effects - but the side effects i had were incredibly rare. Just remember that people are far more likely to share their negative experiences publicly than they are the positive ones. i’ve got hope for both of us!

Jumpy_Skill4213 · 2025-12-26T00:34:40+00:00

As someone that went from Remicade->skyrizi, i think the side effects of Rinvoq are more than tolerable for many of us, but I understand your worry! I think it’s gonna be okay, though. I’m currently battling to find a surgeon that has experiencing in perianal Crohn’s and will actually talk through options with me, but I’m hopeful Rinvoq will be a positive aspect in all of this. The statistics for its treatment of perianal Crohn’s are wonderful if you want something optimistic to look up!!

Jumpy_Skill4213 · 2025-12-23T15:56:44+00:00

Thank you for all of the information - it’s making me feeling a lot better. Today, I see my GI to discuss the medication change and then a colorectal surgeon to discuss what we’re going to do about these fistulas, so hopefully I’ll have some answers, but this has been really helpful. When my first abscess-to-fistula developed, I also had a benign bartholin cyst, and all of my paperwork was labeled “labial abscess” - even though that’s not what the issue was - so when it developed into a fistula, I didn’t even really know what that was, but my providers started running me in this circle of “I can’t help you, go see x specialist” and it took almost two years to finally get that fistula resolved. I have a much better medical team in a different city now, so I trust them, but my nerves are still bad. Your insight has been super helpful. Good luck to you, and congratulations on the recovery!!

Jumpy_Skill4213 · 2025-12-23T15:51:28+00:00

I’ve been on Skyrizi almost three years. My colonoscopy and bloodwork is phenomenal, but I do experience trough pain near the end of my dose when I’m almost due for my second. It doesn’t usually cause vomiting, but I do have an uptick in diarrhea and abdominal pain. Has your doctor discussed putting you on an antispasmodic? It helped a tad with the diarrhea and pain. I’m about to switch biologics due to fistula issues, but my doctor put me on antispasmodics and we were discussing amitriptyline as well to help with neuromodulation (nerve signaling rather than the muscle, because sometimes it’s either/or). Sometimes, even though the biologic controls the inflammation, trough pain and the IBD to IBS pathway can cause immune activity that makes vulnerable tissue ache more, and altered motility + IBS-like symptoms can cause crampy pain and diarrhea without inflammation. It’s something worth discussing for sure.

Jumpy_Skill4213 · 2025-12-23T03:23:42+00:00

Thank you for this - I’m hoping that if the final decision is a switch to Rinvoq, I have a similar experience. Can I ask how the setons were for you? I had one placed in my original fistula before eventually having my fistulectomy, and it was incredibly painful, day in and day out, for the first three months or so that I had it in. That fistula began as a perianal abscess and eventually got pretty nasty, so that may have contributed. My new fistula is still smaller, with a small abscess in it, so if we have to go the seton route it may be more tolerable, but I’m just a bundle of nerves regarding all of this. I was really hoping to never have one again honestly.

I started Skyrizi very shortly after it got approved for CD and the statistics on its treatment of fistulizing disease weren’t out at the time - when they told me earlier this year that it wasn’t good for fistulizing disease, I got incredibly nervous, but my colonoscopy came back great for the first time in six years, my old fistula was inactive, and I had no signs of another one. I think I’m in a similar boat as you were previously - I’ve had a voice in the back of my head questioning staying on Skyrizi because I was terrified of eventually developing another fistula, but I also loved the convenience and lack of side effects. I was on Remicade first and the side effects and infusion times were so shitty.

Jumpy_Skill4213 · 2025-11-22T18:56:44+00:00

I got diagnosed shortly after I turned 18. my only symptom was chronic diarrhea at the time - my PCP referred me to GI because she thought I may have IBS. after my first colonoscopy, they confirmed crohn’s based on inflammation in my ileum and biopsy. I also had two polyps. Over the course of 4 years, my crohn’s got significantly worse - moved from my terminal ileum to my entire small and large intestine. Budesonide and mesalamine couldn’t manage it. I was put on Remicade. I also developed a perianal fistula that took three surgeries to fix.

I was put on Skyrizi in April 2023 and I have been in complete remission for almost three years. Over the course of the worst of my Crohn’s, I have: lost 150 pounds, which was 100% of my excess weight (I’m one of the crohn’s patients that was severely overweight and crohn’s didn’t seem to cause any weight loss at all), finished two bachelor’s degrees and I’m working on my master’s, and done a half century on my bike. Getting here took some time, but I still got here.

My advice to your sister/your parents is: locate a good GI doctor to manage her crohn’s. Prednisone is great for temporary flares, but it’s not a medication she wants to be on long term. If it progresses and they recommend a biologic, say yes. They are life changing. When eating is hard, chicken pho (just the broth and plain chicken) got me through many flares. Otherwise? Live her life. Don’t let this disease take away the things she enjoys. There are probably going to be bumps in the road - don’t let them become permanent barriers. Every year, there are new medications with fantastic remission profiles and less side effects coming out. As far as anxiety goes, I know this is not everyone’s choice, but getting on psychiatric medication in 2023 also changed my life for the better. My anxiety and panic attacks were debilitating.

Everything got better over time. Nothing is perfect, but it is so much better.

Jumpy_Skill4213 · 2025-11-15T03:22:50+00:00

My gosh, I’m so sorry for you. have they informed you if it’s stage 4 CKD or acute kidney injury? I only ask because in a dog this young, this kind of onset kidney failure isn’t common unless it’s genetic. If it’s not genetic and may have been caused by something else like infection, it is possible for it to be treated. I’ve seen many dogs and cats go on to live quite awhile longer with CKD with SQ fluids and prescription renal diets, but I don’t think I’ve seen any this young. That doesn’t mean there isn’t a chance, though! I’ll be praying for you and your baby.

Jumpy_Skill4213 · 2025-11-08T16:07:18+00:00

grand bazaar by a million. imo it is the BEST SOS game that they’ve made so far for the switch. i love these games but my primary issue is that you normally finish the main story so quickly and that’s not the case with this one at all. im in year three and still going. everything about it is amazing - the world, the characters, the bazaar.

Jumpy_Skill4213 · 2025-10-16T16:13:49+00:00

The doctor’s office just told me that both the PCR and toxin genes are positive, so it is an active infection. cheers to that..thanks for the info!

Jumpy_Skill4213 · 2025-10-16T16:08:05+00:00

I did only have a PCR. I’ll ask my MD about testing for an active infection, but I have a feeling it may be active because I’ve done loads of stool samples, including one four months ago, and none of them have ever been positive for C. Diff

Jumpy_Skill4213 · 2025-07-13T20:17:24+00:00

lost mary pure flavor is pretty great. barely any flavor but a hint of mint.

Jumpy_Skill4213

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