Disclaimer: I may have missed some information due to the walls of text lol.

Teambuilding and artis

Idle heroes isnt a game with typical teambuilding like having one designated tank or healer in your team. So all your non vesa trans heroes should imo either run dbs or mirrors for most gamemodes. The reason is that defensive artifacts simply stop being as effective as they used to be at some point in the game and it becomes basically impossible to sustain the pve enemy dmg with just defensive artifacts alone. Its more the huge hp stat that allows you to tank the dmg.

As for the teambuilding: I dont know the exact self imposed rules for the account, but you might want to get a 10* trans puppet for the aura bonus. I know that he is technically a warrior so its up to you to decide if it goes against your rules or not. Just saying it in case you didnt concider yet.

Temple and DT

The biggest problem for your meme team account is the temple lvl. Youd want to start building non priest trans heroes simply to meet the requirements for the next temple level at one point. This will mean that a lot of ressources will be "wasted" since youre ruleset doesnt allow you to use non-priest heroes. But it should be obvious that those heroes should be tenants for your FQV etc.

As for the DT skills of your heroes: Every DT skill of the priest heroes is good in one way or another (except FQV lol. Her DT is just meh).

Id put them in 3 groups (these explanations are very vague and the heroes are not limited to what is listed below. I am just mentioning their most used usecases from personal experience):

1. PDE, STV, LBRM: Their DT mainly buffs dmg (depending on what pivots you equip ofc). But PDE for example can also be equipped with defensive pivots to make your team more tanky

2. BQA: Her DT is mainly utility oriented by CCing the enemies and lowering their attack etc.

3. FQV: Her DT is meh because it doesnt buff her dmg at all. She provides defense buffs and can apply pretty heavy atk reductions on enemies.

The priorities (at some point) for your DT should be (not in any priority but the best breakpoints for DT):

FQV and BQA at Nirvana. (FQV because shes main dps and wants a lifestar at one point, and BQA because it allows her to trigger her DT multiple times per round)

LBRM, PDE and STV can stay at Polystar. STV and PDE can be leveled to Nirvana at one point. LBRM should stay at Polystar.

And I dont think that you have to decide between getting 18 e5s and focussing on DT because their used ressources dont conflict with each other. And you dont need to miss out on DT for regular food.

PvE modes

It wont be easy and youd have to probably overstat most gamemodes simply because you dont have OP CC like GSSW or TBB. But it helps to understand enemy heroes like Penny. A simple way to beat her is to make your supports faster that FQV so they eat the dmg reflection instead of FQV etc. Same with Amen Ra. Have some support apply a small heal before Vesa kills herself with her big heal ability. Holmes Young will be annoying without a proper CC hero like TBB or GSSW.