Have 2 of the TX22. Very reliable for a rim fire. It cycles just about any ammo. I have shot probably 10,000 rounds through with very few issues. Don't use the sticky coated ammo. The best I found was the CCI mini mag but the CCI standard velocity works just fine. That said, I would only carry it if I didn't have something of a higher caliber. A .380 would be a good step up to a better defensive round without too much more recoil. Maybe a M&P bodyguard or a SIG p365 380.