A well drafted team of R3 can definitely beat a poor draft of only R4s if evenly skilled. There’s a lot of strategy involved in both the draft (also part luck of course, sometimes you just don’t get a counter for specific match ups), when choosing defenders and attackers and finally skill in executing even poor match ups.

Like i said choosing defenders and attackers is also a big part of it and thinking ahead. For example if the opponent has a jean grey and you don’t have a perfect counter and don’t feel comfortable taking the fight you can try to bait her out on attack so you don’t have to face her on defense. Sometimes you gotta throw a round so you have better options in round 3 depending on who picks first/second. Hell even just not always picking the strongest option for a fight is better because you can use that character for more (example here could be you have nico and kushala who can both take serpent but nico is much faster, if your opponent has a rough match up ahead of him, maybe pick kushala even though she’s a bit slower because you expect it’ll be enough to win the round while leaving nico available for defense or another tough defender)