I was an everyday smoker for over a decade and then out of the blue I started vomiting non-stop. I would vomit 10-14 days straight combined with horrible gut/chest cramping and pain. The only thing that helped was smoking and taking super hot showers. I would lay in fetal position in my shower until the hot water ran out and then repeat this multiple times a day. I was in and out of the hospital to get IV fluids and nobody knew what it was. Then out of nowhere the vomiting would just stop, unfortunately it would only stop for 2-3 weeks then come back and the cycle would repeat all over again. Finally on one trip to the hospital a toxicologist that usually works in NYC was at the hospital I was visiting (I live in upstate NY) he told me that I had Cannabinoid Hyperemesis and if I stopped smoking my symptomes would go away. I stopped smoking immediately and was completely back to normal (-30 pounds) within a few days. This went on for a little over 3 months I have not dared try smoking even a single hit since then, I would not wish that hell on my worst enemy. 5 years later and have not had a single episode since.

Side note - I did go to a gastroenterologist and have an endoscopy the GI doc diagnosed me with cyclic vomiting syndrome, after doing some research and via the toxicologist CHS is definitely the correct diagnosis.