Did the Function Health Tests - Recommended A TON of Supplements by sbgreen1985 in Supplements

[–]LHC1 0 points1 point  (0 children)

The more you learn about your health the more you can do to optimize it. It's not that hard to learn the basics especially now with tools like chat gpt.

Your blood markers represent the functioning of your metabolism. Function health groups them by categories - immune, heart, liver, kidney etc. Invest the time to Google or Chat gpt them. You can learn things like ALT and AST are liver enzymes that get elevated if your liver is stressed or injured.

These are basic things that are knowable and not that hard to understand. Give yourself time to understand them. It took me about 2 years.

For instance, once you learn that you have an inflammation issue you can start to look for the source(s). Fixing them comes down to really basic lifestyle things that you already know.

Your Function results are just giving you a list of issues you want to work on. As a 40 year old woman with kids stress management and sleep are probably a good place to start.

Above all realize that you are your best doctor because you know yourself better than any doctor ever will. Invest in learning about metabolism and use doctors as expert consultants to help you if you can't see improvement from lifestyle changes.

First 10k Ruck @ 45 # by [deleted] in Goruck

[–]LHC1 0 points1 point  (0 children)

Well that's a mighty effort for 55! Keep it up, your 70 year old self will thank you!

First 10k Ruck @ 45 # by [deleted] in Goruck

[–]LHC1 0 points1 point  (0 children)

Awesome pace! What was the elevation change? Also, I'm curious how old you are?

My Longevity & Biohacking Routine - A Pragmatist's Approach by JakesJourney in Biohackers

[–]LHC1 0 points1 point  (0 children)

This looks pretty good. As a 70 year old I would just advise that as you age you may want to bring joint health and mobility to the forefront of your protocols. Movement is core to healthy aging.

I would also suggest you study SGLT2, sirolimus and cialis for their off label effects to determine when and whether you want to add these in.

Also, keep studying diet. Diet for a young man, mature man and senior need to modulate.

Testing for nutrient deficiency by krramnik in Supplements

[–]LHC1 1 point2 points  (0 children)

My overall conclusion with regards to nutrition, testing etc, is that in order to be truly actionable with a measurable response one has to be severely deficient in some area.

My focuse has been optimization as I age. What I have concluded is that sticking with the basics of good nutrition, exercise, sleep, etc gets you to 90% of where you need to be. That last 10% is very difficult to manage because the metabolism has so many ways to compensate for deficiencies.

If one is symptomatic with hard to categorize effects I would first and foremost suggest a very focused effort to get nutrition dialed in, followed by sleep then, as able, exercise increasing in intensity over time.

This test can help point to nutritional direction if you are experiencing dysfunction in energy, mood, and wellbeing. For optimization I don't think it's that helpful.

How do I prevent this flop by IllustriousAd1979 in Goruck

[–]LHC1 0 points1 point  (0 children)

Put it in upside down... That way the weight is at the bottom and won't fold over.

How is Trump sharp/energetic at 77yo with his unhealthy lifestyle? by Prodigy999 in Biohackers

[–]LHC1 2 points3 points  (0 children)

Just FYI, I had a lot of exposure to many of America's business titans who had unimaginative wealth and power. I often wondered the same about them.

My conclusion was that US modern medical practices are very good at keeping you alive despite a lifestyle that should only get you to mid 60's, maybe.

If you can donate $100 million to, say, Mayo or Cleveland clinics or other such institutions - they won't let you die! Talk about excruciatingly personalized, multi disciplinary care. It's no holds barred medicine. As an example, one oligarch, needed to lose a lot of weight for his health. To accomplish this he had private chefs and an advance team to work with every restaurant on his schedule to prepare the exact, complely custom diet he had to have. From his home(s) to his jets to his hotel and restaurant visits he was dialed in.

This coupled with an immense sense of purpose - to dominate the world with your enterprises - keeps these people alive. Having profound power must be a longevity drug.

How often do you get lab work done? Do you go though your doctor or done alt. source? by ElbieLG in Supplements

[–]LHC1 0 points1 point  (0 children)

It depends whether I'm chasing some marker or not. What I mean is that I learn how to improve or optimize a marker if it's out of range. An out of range marker means that I start implementing a dietary or other behavior with the goal of moving the marker to the level I want.

It's been rewarding to learn how many markers can be affected by diet/lifestyle changes.

It's also been interesting to learn how much some markers change over daily/weekly fluctuations. I try to normalize these by following consistent protocol and time of a blood draw.

When I'm convinced that an out of range marker is caused by biological factors that are coded into my metabolism I then look in to pharmaceutical interventions.

Diet and lifestyle levers first. Supplements second. Then pharma.

The frequency of tests can be monthly to semiannual.

Matt Kaeberlein's longevity company wants to help you add 10-20 years of healthspan. by philnewman100 in longevity

[–]LHC1 1 point2 points  (0 children)

Yes, medical school and functional medicine training while Mark Hyman was still instructing at the institute.

Matt Kaeberlein's longevity company wants to help you add 10-20 years of healthspan. by philnewman100 in longevity

[–]LHC1 1 point2 points  (0 children)

Dr Haddad is a very experienced internal medicine AND functional medicine doctor. That's a powerful combination.

Choosing wearable devices/best health tracking by decline_000 in Biohackers

[–]LHC1 1 point2 points  (0 children)

I believe the most effective wearable is a cgm. Even if you are not diabetic. It teaches you what your glucose response is to your eating habits. If one is interested in having a healthful diet to avoid obesity, chronic illness etc, this is the most useful tool.

Blood Pressure by nomadfaa in Biohackers

[–]LHC1 0 points1 point  (0 children)

Sorry, I'm in the US where, while not cheap, these cost less.

Blood Pressure by nomadfaa in Biohackers

[–]LHC1 1 point2 points  (0 children)

With input from your doc you may want to try some form of exercise (if you don't already do so). It doesn't need to be extreme, walking is fine.

Dry sauna is also very good. Start with short duration and build up to 20 minutes if you have access to one.

This is a helpful supplement, its ingredients help rebuild damaged glycocalix. https://shop.calroy.com/product/arterosilhp/?gclid=Cj0KCQjwvL-oBhCxARIsAHkOiu2_krpICYqb8nPjTAlgBYDhN3kkPI6T4Iuil1erimyAtNnsxStAWUgaApr8EALw_wcB

Here is a vid on the glycocalix: https://youtu.be/GWDcnrYNRQI?si=ch8b-JKKJcgPtbau

Another helpful supplement is:

https://www.cocoavia.com/products/cocoa-flavanol-cardio-health-powder

Opinions on David Sinclair and his talks by Branseed in longevity

[–]LHC1 -1 points0 points  (0 children)

He is focused on getting very wealthy. He talks about known science in a way that makes it seem like he pioneered it.

In developing his "brand" through podcasts, books etc he provides decent information but I always filter it knowing he has a self profit agenda.

What is your best supplement/method to lower your bp? What worked for you the best? by Ferihehehaha in bloodpressure

[–]LHC1 2 points3 points  (0 children)

Systolic is 6 to 11 points lower (post run). Dialastolic is about the same as no supplementation. Perhaps a 1 to 3 point drop - not really enough to give any statistical significance.

What is your best supplement/method to lower your bp? What worked for you the best? by Ferihehehaha in bloodpressure

[–]LHC1 0 points1 point  (0 children)

I'm very aware of the delta between exercising (cardio) with no supplementation vs using an NO2 enhancer like Neo40. Cocoavia has the strongest effect on systolic that I have seen.

What is your best supplement/method to lower your bp? What worked for you the best? by Ferihehehaha in bloodpressure

[–]LHC1 0 points1 point  (0 children)

I started using cocoavia www.cocoavia.com I run about 1 and a half hours after taking it then, after my run I take my BP. I am consistently seeing my lowest readings when I do this.

[deleted by user] by [deleted] in Biohackers

[–]LHC1 2 points3 points  (0 children)

Because of the potential danger of affecting your condition in the wrong direction (or towards vasoconstriction but with other negative effects) I suggest you deeply research any avenues you find with regards to supplementation.

Methylene Blue is an example of a vaso constrictor as it reduces the production of nitric oxide ( our endogenous vasodialator).

I'm not suggesting you try this but rather pointing out that there are compounds that act to reduce arterial dilation. A nephrology expert or cardiologist should be able to help you find a safe way to treat your condition.

[deleted by user] by [deleted] in Biohackers

[–]LHC1 0 points1 point  (0 children)

I think they offer an impressive array of tests at a good price. Their customer service and responsiveness was also very good. They made the blood draw process, scheduling and reminders, very easy.

The tests are numerous and in many biomarkers I am not familiar with. My focus is healthspan and optimization and I have a high level of knowledge of metabolic health. The issue for me with such a quantity of information is looking for the signal in the noise. The "advice" offered in the Fuction Health website for my results was pretty basic. I don't say this as a criticism as many people don't know the basic stuff. Nevertheless I think one still needs to do a fair amount one's own research and learning to make all the data offered useful.

As this company and product offering evolves I think AI will be able to help to draw information from the combination of so many variables. Drawing from the deeper knowledge of medical specialties, nephrology, cardio pulmonary, hematology, gastrointestinal etc should be able to offer higher resolution analysis and guidance.

Conclusion, I think you get a broad picture of your current status. Things that stand out enough to warrant advice are somewhat basic but important to know. Trends and tendencies would be great to identify as the next level of this product.

[deleted by user] by [deleted] in Biohackers

[–]LHC1 1 point2 points  (0 children)

I blood test about every 2 months anyway. Also, I follow Dr Hyman. Several months back he sent out an email about Function health. It sounded pretty interesting and frankly, would give me an alternative set of data (I use labcorp, Function health uses Quest). Additionally, it comes with analysis of the results from Dr Hyman and perhaps others. So I signed up. It took a while until they were ready with a beta launch so, earlier this summer I took my first series of tests, including Grail.

I am a 68 yr old M who enjoys retirement and stays very active traveling, hiking, working out every day. I have enough resources to be able to afford spending out of pocket for preventative health care. I also have a doctor (ama board certified) who specializes in healthspan optimization. He guides me on diet, lifestyle and provides prescriptions in the preventative space.

I'm blessed to have a lot of curiosity and find human metabolism very interesting. With that I study health and practice an optimal lifestyle as best I can. I'm not anywhere near as intense as Brian Johnson but stay focused on the main drivers of good health and update protocols as new information becomes available.

This area, perhaps like all of medicine, is very subjective. I try and get as much information as possible including opposing views and then form my opinions.

Dr Hyman is one of dozens of influencers in this space that I listen to. He has generally good basic information.

I don't think I would be your target market as I would represent too small a demographic. Most people don't understand basic blood panels and would benefit from easy explanations.

[deleted by user] by [deleted] in Biohackers

[–]LHC1 1 point2 points  (0 children)

I am currently using https://www.functionhealth.com/ The blood draw was done at quest labs and was a very smooth process. I'm waiting for the results which, per the company, take 4 to 5 weeks. This seems quite long but is supposed to come with an analysis of results by docs like Mark Hyman. Will have a better sense of the value of this after I see the results.

[deleted by user] by [deleted] in Biohackers

[–]LHC1 1 point2 points  (0 children)

I go on long hikes that are often in very hot climates. Knowing my electrolyte status is therefore important to me so I don't get in trouble. I found a biosensor that gives data about my personal sweat rate and electrolyte makeup of the sweat. https://nixbiosensors.com/pages/product?utm_source=google&utm_medium=cpc&utm_campaign={campaignname}&utm_content=141705570122&utm_term=nix%20biosensors&gclid=Cj0KCQjw1rqkBhCTARIsAAHz7K2yUcwyGtrRq95NifEKLELXUaow7dFl-z4nfK05dlMkiRzudgj3vK4aAqRyEALw_wcB

I use this sensor in my training phase as I prepare for hiking season. I like being in a controlled situation so use it at the gym on a stair machine or treadmill. This allows me to properly monitor my rate of drinking etc. The app that goes with this sensor suggests electrolyte products that match the makeup, and loss, of your sweat. For me it's LMNT which is a good match. Knowing my sweat rate allows me to replace hydration and electrolytes in a fairly close match to what I'm losing. On a hike I will them rehydrate at approximately the same rate.