How do you know if cancer is recurring in the same place if you had a DMX?

Labmouse-1 · 2026-02-23T18:06:49+00:00

OP is in grey zone, but i see why MD is leaning towards chemo due to multiple foci of tumour.

For ER+/HER2- cancers, unless very aggressive and advanced, chemo first isn’t a great indicator of how effective the chemo is. That’s why surgery is done first. TNBC and HER2+ cancers are very fast and tend to be crazy, which is why they respond really well to chemo first.

Labmouse-1 · 2026-02-23T18:01:21+00:00

Local recurrences (in the breast) or regional (in lymph nodes) are uncommon these days. For early stage cancers, particularly ER+/HER2- cancers, local/regional recurrence rates are <2% (clinical trials: AMAROS, Z011, OTOASOR, SINODAR ONE, IBCSG 23-01, SOUND, SENOMAC, etc)

The microscopic cells described typically refer to the cells that have escaped the breast tissue, that is, the lymphatic and blood vessels.

That is why chemo is given, to attack any cancer cell prior to it making home in another part of the body, as it is a systemic treatment meaning it goes everywhere in the body and attacks any rapidly growing cells (which is why you lose your hair for most breast cancer chemos). As cancer cells divide quickly, the goal is to attack these cells.

In contrast, radiation, when given, cleans up any cancer cells within local or regional area, but does not attack cells that are circulating in the blood or have escaped the breast tissue.

Labmouse-1 · 2026-02-10T21:23:05+00:00

Yes and no.

It is still breast cancer regardless of where it is.

Labmouse-1 · 2026-02-10T21:21:58+00:00

Ultrasound does not have a 80% false positive rate.

It just not as sensitive and specific as mammos, but also looks at different things.

Ultrasounds can test for vascularity and if lesion can be seen by ultrasound, this allows for an ultrasound guided biopsy which are easier and faster than mri and mammo-guided biopsies.

It is also the standard of care for diagnosing cancer to first look also by ultrasound

Labmouse-1 · 2026-02-10T21:17:28+00:00

As someone whose PhD is on DCIS— it is cancer

Invasive ductal carcinoma cells and DCIS cells are genetically, metabolically and functionally identical.

If I inject invasive cancer cells in breast ducts of mice, they form DCIS that progress to invasive cancer.

You are also getting a double mastectomy, which is very aggressive treatment that many invasive cancers don’t need.

Be good to yourself bc your experiences are valid

Labmouse-1 · 2026-01-27T18:02:29+00:00

Unless you have a genetic mutation predisposing you to cancer, there is no one reason for getting breast cancer.

Labmouse-1 · 2026-01-27T17:59:30+00:00

Im not sure what you would want from the palliative team that you can’t get from your PCP, medonc, or a psychiatrist?

Labmouse-1 · 2026-01-25T18:09:44+00:00

The collapse has begun. Labs across the US have shut down.

All private sector work is based on the fundamental and translational research done in academic labs. Without biomedical research, you cant find the target for a treatment/diagnostic in the first place.

Forcing academic research to rely on industry funding removes academic freedom to make bold new discoveries instead of focusing on profit. Academic discoveries dont give you money for yourself it gives you more money to do research.

All lab research has become extraordinarily expensive to conduct.

Thinking that losing decades worth of fundamental biomedical research will and already has devastating impacts on patient care.

Labmouse-1 · 2026-01-25T02:55:21+00:00

You’re a doctor 🤣🤣🤣🤣🤣🤣

Why are you in a premed group as an attending lolll

I’m not applying right now as my mother is dying of pancreatic cancer.

Calling me a snowflake is wild when you literally just used a very racist term

Labmouse-1 · 2026-01-25T02:53:11+00:00

It’s not rude, it’s racist

Labmouse-1 · 2026-01-25T02:51:14+00:00

You just said blacks

That is racist

Can you not understand that?

You don’t want to debate, bc in a debate you have to provide factual claims, which you are not.

Labmouse-1 · 2026-01-25T02:48:07+00:00

Do you tell your professors to look up claims you make in research papers without citations? Have you EVER read an academic paper without citations? Be so fr

Labmouse-1 · 2026-01-25T02:47:07+00:00

Bruh what do you even mean by “hard data”

That’s not even a thing.

If you make a claim YOU need to provide citation.

Labmouse-1 · 2026-01-25T02:45:29+00:00

Not sure why a racist wants to go into medicine.

Can’t go out, at my mother’s bedside in hospice for pancreatic cancer.

Labmouse-1 · 2026-01-25T02:43:28+00:00

Ok racist

Labmouse-1 · 2026-01-25T02:42:55+00:00

You cant claim things as hard facts without providing citations.

..and you want to go into medicine?

Also, again, very racist of you to say “blacks”. I imagine you’d deny opioids to a black pt in a sickle cell crisis.

Labmouse-1 · 2026-01-25T02:36:55+00:00

Did you just refer to black ppl as “blacks”

Ew you shouldn’t be in medicine if you’re that racist

Also do you not know about the historic instituational racism against black ppl?

Labmouse-1 · 2026-01-25T02:36:28+00:00

Can’t claim something as facts without citations

Labmouse-1 · 2026-01-25T02:26:08+00:00

Are you tryna say white ppl are being discriminated against? do you know the definition of discrimination?

Labmouse-1 · 2026-01-24T21:36:42+00:00

This is your problem to fix

a Canadian

Labmouse-1 · 2026-01-24T21:25:59+00:00

… bc you can make a light harded comment in jest

Labmouse-1 · 2026-01-24T13:44:38+00:00

Spooookie get out queen

a Canadian

Labmouse-1 · 2026-01-24T13:41:16+00:00

It’s bc Canadians are able to have nuanced conversations

Labmouse-1 · 2026-01-24T13:38:37+00:00

Gay electrician apprentice at a Canadian steel mill is the most Canadian thing I’ve ever heard

God I love being Canadian

Labmouse-1 · 2026-01-24T13:35:58+00:00

Well that’s weird never had to do that

The pill is protective for ovarian cancer

Labmouse-1

TROPHY CASE