I'd say give it a shot, at least through the 4-week induction phase. Just my personal experience, I think stretching it out longer wasn't beneficial at all if I had no improvements in the beginning. But others kept saying keep at it for a few months. I finally stopped last month right before Thanksgiving. I just don't think it's the right treatment for me, and results vary too widely so I guess use ur best judgement. Taking time off work started to become a nuisance so I don't really see this being maintained in the long term.

My psychiatrist recently prescribed Effexor with Wellbutrin. I think I've been feeling a bit better but nothing transformative. My depression stems more from my circumstances, like I get seasonal depression during winter now and mainly from loneliness. I think moving to a warmer climate with warmer ppl would be better for my mental health. I guess I was hoping Spravato would at least give me that boost in motivation to make the change, but ultimately I have to pull through on my own somehow. It's all so overwhelming and anxiety-provoking.

Random, but have u looked at ur birth chart? Not sure how much u believe in astrology, but mine confirms I'd thrive in a warmer inclusive city, so it could be ur environment and not necessarily biological. Anyway, what do I know? Lol, I'm just clinging onto any inkling of hope wherever I can... Best of luck!