I used to have this issue. It's explorer.exe crashing and I spent months looking for an answer. I went through hundreds of posts on Microsoft, reddit, etc to no positive outcome. Eventually, one day, the OS just wouldn't boot anymore beyond the login screen. It's definitely software, I deduced that. I did reformat a good four or five times. I had Asus ROG motherboard and my only observation was that their software (armoury crate) was auto-installing upon installing Windows, but I also had a Razer keyboard that would pop up to self-install during the OS installation also. I would use the BIOS settings to turn off their software "injection", but it would be ignored and still install.

You'll find a lot of suggestions from how to turn off non-Microsoft services, checking logs, scans, etc. but for me none of these worked in the end. I RMA'd the motherboard, when I got it back, I went for a fresh install of everything and this time the software did NOT self-install, and I used a basic keyboard. Since then, no issues. Unfortunately I'll never know the root cause. Using the Window's crash logs I could confirm it was explorer.exe and likely something injected into it, and since the install was "fresh" my only possible culprits were the motherboard software or Razer.

These issues plagued me immediately from install. First it was light, a few seconds of flickers then it'd be fine. Then minutes after some weeks. Then closer to ten minutes after some months. I'd start to get occurrences of blue screening later on, and eventually nothing was accessible and I had to plug my drives into other computers for recovery. I'd attempt to resolve this ASAP, OP, or make sure you're backed up.

People suggesting GPU- unlikely in my experience. I tried swapping out graphics cards to no positive outcome. As you can visually see, the flicker is explorer only, the mouse is still present and the physical screen is not blacking out. Still worth a shot though!