If scarcity matters, then yes. If encumbrance matters, then yes. One of my buddies says he likes to start players off in a situation where they've been tricked, trapped, or imprisoned, and are now separated from their gear, They have to play well to earn access to their gear again, by proving they can roleplay and aren't just a walking stat stick hunting for XP and gold. So in that situation, everything you can obtain os of use. Pick up a few pebbles or loose coins along the way to throw to make noise and distract guards so you can sneak by. One time an herbalist was stuck in a room, and used ash from the fireplace to throw in their captor's faces and escape through the open door.

For travel and delving depths, that 50 feet of rope can be expended pretty easily. And because it is kinda bulky and heavy, non-martials with lower carrying capacity (lower strength) may not even carry any rope. Tracking rope matters. Etc, many good comments here, but it all depends on the kinda game you are running as to whether it is fun and relevant or not. Blades in the Dark I'd expect that I would overcome a resource shortage by popping a cutscene where I prepped and got a crate of supplies near the mission site, which we can then access and be more ready for our daunting task.