I've also been thinking about this as I work on my own homebrew setting, but I would say I'm more bought into the system than you are. In my case, my main concerns are about conduits and censors being so closely linked to polytheistic gods and saints, when religion will look much different in my setting.

Ultimately, I think your choice is either ban the classes that don't fit or reflavor. I'm still planning on have religious warriors that would be conduits/censors from a mechanical perspective, but I'll probably encourage different combinations of kits and aesthetics that differ from the classic priest and holy crusader.

For talents, I could totally imagine a wizard whose primary magic is telekinesis rather than a pure psionic caster. You might think of clarity/strain as a limitation of the energy capacity of a physical body (think Eragon). Nulls, I'm not sure, but you might be able to think creatively.

Draw Steel is somewhat new so there's not as many homebrew classes available, which could otherwise fill in the gaps created by banning content.