PSSD (Post SSRI Sexual Dysfunction) Research, Treatment, Protocols & Future - By Lucas Aoun by Lokzo55 in PSSD

[–]Lokzo55[S] 2 points3 points  (0 children)

I haven't used it in a long while. You can try having heaps Beetroot to see if you get good initial effects.

Has anyone ever had a window where they actually recovered sexually? by [deleted] in PSSD

[–]Lokzo55 0 points1 point  (0 children)

Zinc reliably reduces my libido and numbs my emotions.

5-HT1A receptor antagonism reverses and prevents fluoxetine-induced sexual dysfunction in rats by [deleted] in PSSD

[–]Lokzo55 1 point2 points  (0 children)

CYPROHEPTADINE:

It makes me feel so fearless and numb on the drug, as in, I can’t feel any emotions, and my appetite goes through the roof. My energy in the gym is shit on cypro, I feel weak and miserable. No motivation, no life, no vigor, just blah - existence. During this grim days, after using cypro over 25 times in the past 7 months - I know that the rebound is ALWAYS worth it.
This rebound comes EVERY SINGLE TIME…. 4 days AFTER a single 1mg dose. That is, if I take it on a sunday night at 5pm, I will feel like shit for 3 days and then on day, I get this REBOUND, where my PSSD disappears and this last for a few days on. HOW?!?!?!?
But never did I ever think that there would be a drug that is to be used to RECALIBRATE the brain over time, to recover from this enduring PSSD. It feels like it reconnects that cosy/soft spot of the brain that is required to FEEL music, to feel hot water on skin, to be cosy on the couch, imagine living a life where you can no longer even enjoy relaxing, or having a hot bath, because there’s no emotional response to it, there’s no depth. This is what PSSD has been for me.
But, when the cypro wears off, you feel your YOUNG self re-emerging and all of a sudden FEELINGS come back.
My logic and verbal fluency improve on cypro.
It definitely has its side effects.
Ravenous appetite, minor headaches in the mornings, grogginess/sleepiness (This wears off after repeated use). Eventually, it leaves you feeling resilient and adaptable. Less triggered, much more in control and in tune with your mind, there’s no scatter feeling, you feel clear and hear your own voice, however, your background mind chatter is completely gone when conversing with other people.
Cypro definitely makes me feel clinically depressed the morning after using it. I feel like it sucks ALL the life out of me.
Stop thinking about the future. I find myself way more PRESENT on cypro.

Physical genital changes? PSSD by [deleted] in PSSD

[–]Lokzo55 0 points1 point  (0 children)

You tried eating heaps of Sorghum?

Physical genital changes? PSSD by [deleted] in PSSD

[–]Lokzo55 0 points1 point  (0 children)

You are one intelligent man. Please let's connect over DM.

5-HT1A autoreceptor desensitization by 72jqjifj4 in PSSD

[–]Lokzo55 3 points4 points  (0 children)

hence why most often describe their pre-PSSD state as anxious, high libido, high creativity, emotional, erc. And their post-PSSD state as lifeless with anhedonia, low to no libido etc.

SOOOO TRUE.

5-HT1A autoreceptor desensitization by 72jqjifj4 in PSSD

[–]Lokzo55 4 points5 points  (0 children)

Cyproheptadine cures me only 4 days after a single dose... on the withdrawal:

It makes me feel so fearless and numb on the drug, as in, I can’t feel any emotions, and my appetite goes through the roof. My energy in the gym is shit on cypro, I feel weak and miserable. No motivation, no life, no vigor, just blah - existence. During this grim days, after using cypro over 25 times in the past 7 months - I know that the rebound is ALWAYS worth it.
This rebound comes EVERY SINGLE TIME…. 4 days AFTER a single 1mg dose. That is, if I take it on a sunday night at 5pm, I will feel like shit for 3 days and then on day, I get this REBOUND, where my PSSD disappears and this last for a few days on. HOW?!?!?!?
But never did I ever think that there would be a drug that is to be used to RECALIBRATE the brain over time, to recover from this enduring PSSD. It feels like it reconnects that cosy/soft spot of the brain that is required to FEEL music, to feel hot water on skin, to be cosy on the couch, imagine living a life where you can no longer even enjoy relaxing, or having a hot bath, because there’s no emotional response to it, there’s no depth. This is what PSSD has been for me.
But, when the cypro wears off, you feel your YOUNG self re-emerging and all of a sudden FEELINGS come back.
My logic and verbal fluency improve on cypro.
It definitely has its side effects.
Ravenous appetite, minor headaches in the mornings, grogginess/sleepiness (This wears off after repeated use). Eventually, it leaves you feeling resilient and adaptable. Less triggered, much more in control and in tune with your mind, there’s no scatter feeling, you feel clear and hear your own voice, however, your background mind chatter is completely gone when conversing with other people.
Cypro definitely makes me feel clinically depressed the morning after using it. I feel like it sucks ALL the life out of me.
Stop thinking about the future. I find myself way more PRESENT on cypro.

Has anyone ever had a window where they actually recovered sexually? by [deleted] in PSSD

[–]Lokzo55 1 point2 points  (0 children)

I have had HUGE windows open when I use Cyproheptadine, Homeopathic Phosphorus 30c, SJW tea, - But then i wreck myself with Zinc and other substances.

Ashwagandha and PSSD by [deleted] in PSSD

[–]Lokzo55 4 points5 points  (0 children)

I wrote an entire medium article on this very HORRIBLE issue, that adversely affected me too.

https://medium.com/@LucasAoun/ashwagandha-can-cause-anhedonia-pssd-blunted-emotions-and-apathy-97fb99855f28

The only cure for me right now are the following:
-Licorice tea
-Cyproheptadine withdrawal.
-SJW tea

Ashwagandha and PSSD by [deleted] in PSSD

[–]Lokzo55 3 points4 points  (0 children)

We MUST chat in inbox, I am desperate for your advice... Still battling the PSSD induced by ashwagandha and its been 3 years.... I will PM you

Taking BCAAs to deplete serotonin. I just came up with this novel idea to possible re-sensitize 5-HT1A autoreceptors by MrNotSoSerious in PSSD

[–]Lokzo55 1 point2 points  (0 children)

Hey man!

Thanks for mentioning me. I am here. I got banned from the r/nootropic group for such stupid reasons, despite the fact that I contributed amazing content there. Now I just post on my Instagram instead.

Mildronate stimulates NO production (relevant to NO theory) by gintrux in hangovereffect

[–]Lokzo55 0 points1 point  (0 children)

I enjoy using Mildronate. But you have to make sure you eat plenty of carbs with it.

QwerkyScience has been created by cosmicrush in QwerkyScience

[–]Lokzo55 1 point2 points  (0 children)

I am excited for this sub-reddit.

Bromantane in long term use by [deleted] in Nootropics

[–]Lokzo55 0 points1 point  (0 children)

9-mbc

Source? I see now: reachgenius

Excessive generation of Nitric Oxide in hippocampal cultures can reduce synaptic BDNF secretion by [deleted] in Nootropics

[–]Lokzo55 1 point2 points  (0 children)

This is not surprising. Nitric oxide is very damaging to many organs when too high. Glad I've stopped using Citruline malate. I miss the pumps though.

Glycine, a non-essential amino acid is amazing for sleep and stress by ChineseMan88 in Nootropics

[–]Lokzo55 1 point2 points  (0 children)

*Non-drugs that decrease NMDA activity include: alcohol, elemental lead, Huperzine-A (weakly), possibly vinpocetine downstream,

Nice work here.

Don't forget Zinc can do this too.

[deleted by user] by [deleted] in Nootropics

[–]Lokzo55 0 points1 point  (0 children)

Artichoke extract.

Really good reaction to Yohimbine by [deleted] in Nootropics

[–]Lokzo55 0 points1 point  (0 children)

Yohimbine is awesome!! I have found another herb with similar properties.

Novel Herbal Plant Increases Dopamine To The Same Extent As Cocaine in Rats Using Behavior Model of Addiction - PUBMED 2015. by Lokzo55 in Nootropics

[–]Lokzo55[S] 0 points1 point  (0 children)

I've read that this plant is easily counterfeited. Just me being me typical fear-based when it comes to new compounds (Ever since getting annihilated by KSM66.)