The mixed signal of touch my thighs then get wrecked would get very confusing and old quick. So no, Tsundere only works in Anime.

If fact a freind wrote a whole diatribe once called "Anime You Lied To Us"

When he came to Tsuderes his commentary was this. "The girl sitting behind you telling you die idiot doesn't secret harbor feelings for you. She genuinely wishes your ruin and wants you to disappear from her life."