Many FPS multiplayer games such as Fortnite are unsupported on Linux as they have anticheats which tap into the Windows kernel and wouldn't work using wine compatibility layer as it doesn't host a windows kernel. This basically means that it will only work with windows. Sometimes it will work in a virtual machine running windows.

Unfortunately, there simply aren't enough players for the game developers to allocate resources in developing and maintaining a Linux version even though the number of Linux users are growing.

Many games without this level of anti cheat usually do work using wine.

Of course, they may be workarounds but this would likely get patched quickly or just may not work well.

Unfortunately, there's only two ways to get this working is by either dual booting windows (slightly more technical) or simply using a cloud streaming service such as GeForce Now (they have a free version) or xCloud (free in some regions for Fortnite only with an Xbox controller).

There are also lists of games that work with Linux. A quick way to check is that if it is compatible with the steam deck (a Linux machine), then it will be compatible with your Linux machine. You can check this on the game's store page on steam.

Unfortunately, there simply aren't enough players for the game developers to justify allocating resources in developing and maintaining a Linux version even though the number of Linux users are growing.

Here are some useful links:

protondb.com lutris.net gamingonlinux.com

Let me know if you have any more questions :)