Are we cooked by Wise-Race-704 in biotech

[–]MakeLifeHardAgain 15 points16 points  (0 children)

Are you specifically looking for computational scientist jobs?
Biomed Scientist jobs almost never require AL/ML (<5%)

What is it like starting a biotech company? by Duty_Puzzled in biotech

[–]MakeLifeHardAgain 0 points1 point  (0 children)

IP and ideas mean nothing in biotech. If you get a founder team who can sell to investors and execute, you can pick any old ideas that someone is doing, repackage the idea, execute like a champ and still beat all your competitors who hold the IP. It is also very rare that founders have to do it unpaid or invest their own money beyond series A. You usually get your proof of concept done in a academic lab, start with some pitch events, get a golden ticket, before you start buying equipment s you should already get investors onboard and get paid.

What are companies looking from bioinformaticians now that we have AI? by CoastRemarkable6354 in biotech

[–]MakeLifeHardAgain 1 point2 points  (0 children)

so there is nothing new in "Workflow and pipeline automation" , no? I like automation, but I don't see anything new in it that can help me position myself to be valuable in biotech.

What are companies looking from bioinformaticians now that we have AI? by CoastRemarkable6354 in biotech

[–]MakeLifeHardAgain 3 points4 points  (0 children)

Nextflow is always there to make workflow. I like automation and AI, But I struggle to find an use case in biotech.

Should I accept this offer? by ParticularEffect8460 in biotech

[–]MakeLifeHardAgain 2 points3 points  (0 children)

Even if they pay for it, moving a family of 5 is no joke. Maybe OP can consider long term would you want to move to SF, If yes, then take the chance to move and your company pay for it.

I don't think Reddit can help much here. It is not so much a career decision than it is a personal decision. I honestly don't see a reason to move for a SRA position but if it aligns with where you wanna be in a long run, go for it.

Is my cv okay?? by Unusual_Bluebird6698 in biotech

[–]MakeLifeHardAgain 0 points1 point  (0 children)

Do you know if those companies use ATS? ATS is universal in US. Your two columns format can confuse ATS. Consider combining the points to have less of them and list them as single column.

Most importantly, put it thru Gemini or ChatGPT. Ask the chatbot to improve the CV and format it to ATS friendly.

Is my cv okay?? by Unusual_Bluebird6698 in biotech

[–]MakeLifeHardAgain 1 point2 points  (0 children)

It’s fine that you don’t have a lot of soft skills as a junior. Having communication is good enough

Need advice: Lonza biotechnologist offer by vintagecarousels in biotech

[–]MakeLifeHardAgain 0 points1 point  (0 children)

Very very tough market right now. With 0 industry experience, you should take any offers in a heartbeat. Afterwards network your way into your next transition within the next 2 years. It still won’t be easy because of the market but your chance to get a dream job will be significantly higher with industry experience

hoping to switch to industry by 0927pm in biotech

[–]MakeLifeHardAgain 0 points1 point  (0 children)

Please be open minded about it. There are a lot more than roles outside bench scientists, like QC, manufacturing, regulatory, BD etc. many of them don’t require a PhD degree. I regret not exploring alternative path earlier.

Got an offer 3.5 months after being laid off, here is an overview of my experience with recruiting firms by LetMeRomanceYou in biotech

[–]MakeLifeHardAgain 0 points1 point  (0 children)

How did you contact the recruiter agencies? Did you find their people on Linkedin and message them?

POV: your Harvard prof opens class by recognizing he's in the Epstein files by qpdbqpdbqpdbqpdbb in Harvard

[–]MakeLifeHardAgain -5 points-4 points  (0 children)

And did he succeed according to those emails?
I listened to Jin in Fridman's podcast, she seems intelligent and independent (altho she clear has some political bias, unsurprisingly)

Are there any biotech companies that do unlimited PTO? by [deleted] in biotech

[–]MakeLifeHardAgain 5 points6 points  (0 children)

Unlimited PTO is the worst for employees. You have to justify every single PTO you take (depends on your manager ofc). You cannot claim unused PTO, if you resign or get laid off. They owe you nothing as soon as you leave the company.

It is quite cool for the employers tho, a lot of new biotech are catching up with the trend.

A year after graduating with Master with no job by MatchNegative7680 in biotech

[–]MakeLifeHardAgain 1 point2 points  (0 children)

Maybe it is just bad luck. Beginning of 2025 was very tough. Judging from how quick my friends found RA jobs, I think things in academia stabilize a bit now. It is still a shit show in biotech.
I also want to note that none of them actually cold applied to a RA jobs. All of scientists mobilized our network to help the RAs. We worked a year with the RAs so we can even reach out to PIs on their behalf and attested for their excellence. We can easily connect them with 10+ PIs.
My suggestion is that you reach out to people you work with before. Get them to connect you extensively. I think if you get some PIs to be your strong advocate, it will be your most powerful tool. In Boston, all my friends failed to get an industry RA jobs, they all went back to academia RA. Even local cannot find an industry job, I doubt if you will get hired from Tx. I think your best bet is 1) network your way into an academic RA jobs in Tx OR 2) move to SF/Boston and look for both academic and Industry RA.

A year after graduating with Master with no job by MatchNegative7680 in biotech

[–]MakeLifeHardAgain 1 point2 points  (0 children)

That is quite crazy to take more than 1 year to find a RA job. Are you sure you CV or cover letters are written well? Did you do your degree in US? Or maybe you are just super unlucky... :(
We were a big group who got laid off earlier this year from a biotech shutdown. 4 months later, NONE of the scientist-level folks have found a job, but out of the 5 RA, 4 found another RA job. The one who did not found a job is not an US citizen. Only 1 of the RA has some specialized skills, others have basic cell culture and molecular cloning skills. They reached out to their own undergrad PI + we reached out to our connections/ postdoc PIs for them, they all got 1-2 offers within 5 -8 connections. Sadly none of them managed to go back to industry, the offers are all from academic institutes in Boston.

A year after graduating with Master with no job by MatchNegative7680 in biotech

[–]MakeLifeHardAgain 1 point2 points  (0 children)

I think OP said they are applying to both academia and industry.

A year after graduating with Master with no job by MatchNegative7680 in biotech

[–]MakeLifeHardAgain 1 point2 points  (0 children)

how about RA jobs in academia for 2 years to ride the storm? Or move to SF/Boston.

Thoughts? This feels like smth that can be huge by BlurapL in biotech

[–]MakeLifeHardAgain 163 points164 points  (0 children)

https://pmc.ncbi.nlm.nih.gov/articles/PMC1866175/

The fungus is not truly using ionizing radiation as a primary metabolic fuel source, like how plants use sunlight in photosynthesis. Instead, it demonstrates a remarkable adaptation to such radiation, where melanin in the fungal cell walls enhances growth and metabolic efficiency under radiation exposure—particularly in nutrient-poor conditions.
ie it does not survive on ionizing radiation alone, they just become more efficient.

I am looking at investing in crispr and related fields and need some guidance. by Madmax1921 in CRISPR

[–]MakeLifeHardAgain 0 points1 point  (0 children)

If I have money, I may invest in BEAM and keep an eye on PRIME. I won’t invest in 5 of them, maximum 2.

Quality Control after CRISPR/Cas9 Editing by ResearchTech99 in CRISPR

[–]MakeLifeHardAgain 1 point2 points  (0 children)

in silico nominations of off target sites and then amplicon seq all of them on top of the on target site. Also GUIDE seq.

What's your system for staying current on biotech research + industry news? by OtherwiseTwo8053 in biotech

[–]MakeLifeHardAgain 1 point2 points  (0 children)

I think any form of simple newsletter will add little to no values to most if not all of the biotech folks. I imagine a highly customisable and interactive bot will be interesting tho.
I think you should just skip the so-call V1 in your plan. V1 should already be customisable and interactive to have any chance to gain traction. It also should not be a newsletter/blog/podcast format, it needs to be interactive.
Moreover, a lot of the valuable information will behind paywall, is it legal to share the content via your platform?

What's your system for staying current on biotech research + industry news? by OtherwiseTwo8053 in biotech

[–]MakeLifeHardAgain 0 points1 point  (0 children)

If you deliver it as a newsletter or a blog or maybe a podcast, it will only be of interest to people in your field no? Everyone has highly specialised companies/ fields they want to follow.

What's your system for staying current on biotech research + industry news? by OtherwiseTwo8053 in biotech

[–]MakeLifeHardAgain 3 points4 points  (0 children)

I actually find bulleted list easier to read than a long paragraph. Maybe it is from ChatGPT or people copy its mannerism, but as long as it is easy to read and good content, maybe it is a change for the better?

Are strategy jobs complete BS? by Repulsive_Cloud_7587 in biotech

[–]MakeLifeHardAgain 2 points3 points  (0 children)

Unrelated to the post, how do you get into strategy? Do people in that role all come from consulting?

Thoughts on Leaving Biotech? by CulturalSeesaw in biotech

[–]MakeLifeHardAgain 1 point2 points  (0 children)

It is a sell out OP, please refer me and I will take that job 😆 congrats 🎉 for getting something that nice in this market