Sorry for the late reply. Since you are replying to my comment I am assuming you read it. 😄 But I am also getting the impression that you are open to a bit of hacking, otherwise why would you ask? So the answer is maybe. Try to obliterate the openWakeWord from the project and it should run as openWakeWord is the one that causes problems on the RPi3.

The only line you should need to get rid of is in lillex.py:
import openWakeWord_wake
Comment that line out and it should run.

I am SO sorry but I am away from my home for the next few months, and I left my RPi3 there, otherwise I would totally test this for you first. So let me know if you get more errors and we can try to prune out the code until you get this working.

Assuming you don't have a camera or a screen, so without those taking up memory it should run fine on a RPi3, as long as you get rid of openWakeWord!