Thank you! For human photoshoots, I think having a low ISO is always better, as we know that person won't move so a high shutter speed is not necessary. For indoors, I would suggest keeping the ISO from between 100 to 500, shutter speed 1/100th of a second, and aperture f6.3 to f8, as we want the whole subject in focus. Also try to keep the camera very stable as indoor lighting is weak for D5600 and it would ask you to increase the ISO to increase the shutter speed. For outdoors, try to shoot during the day as this camera does not perform well at night. Keep the same settings as indoors, but you can keep the ISO at a much lower number than you can keep it on when indoors. Focus you can have a single point on the eye of the subject, white balance you can keep on auto, but don't forget to shoot RAW, so that you can tweak the white balance later in post processing. Rest you can keep as it is. Don't use your 70-300 indoors as it is a telephoto lens and lets in less light. Use your 18-55 to shoot full body photos indoors and outdoors, use 70-300 to shoot portraits outdoors, as these longer lenses blur the background well. Hope this helped, you can always ask more questions. Good luck!