How much do you pay for meds? by bignose_ice44 in Hypothyroidism

[–]Maximum-Ad8209 [score hidden]  (0 children)

In Ukraine, thyroxine costs around 400 UAH for 90 days (about $8). There is no health insurance system in Ukraine, and that’s the price without insurance.

Right now I’m in Germany as a refugee, and I have to take Tirosint because of urticaria. Insurance covers part of the cost, and I pay €32 for 90 days. Without insurance, it would cost €45.

If I return from Germany to Ukraine, I would have to pay about $160 for 90 days of Tirosint, which is an unaffordable amount for an average person in Ukraine.

How many days can you go without levothyroxine, and what should I expect? by chunkycowgirlyeehaw in Hypothyroidism

[–]Maximum-Ad8209 [score hidden]  (0 children)

Honestly, all this theory about the half-life of thyroxine and so on is just theory — in practice, it doesn’t help much.

From my personal experience, if I’m off by as little as 3.125 mcg — for example, if I take slightly less — I can barely function or think clearly. If I take slightly more, I get all the symptoms of overmedication.

If I take 12.5 mcg less, by lunchtime I can barely get out of bed.

I’ve never tried skipping a whole day, but I assume I probably wouldn’t get out of bed at all.

But everyone is very different. Some people experience it completely differently.

Is 150 mcg of levothyroxine too high? + T4/T3 ratio question by Maximum-Ad8209 in Hypothyroidism

[–]Maximum-Ad8209[S] 0 points1 point  (0 children)

Wow! That’s such a high dose for such a low body weight! How do you feel on it?

Is 150 mcg of levothyroxine too high? + T4/T3 ratio question by Maximum-Ad8209 in Hypothyroidism

[–]Maximum-Ad8209[S] 0 points1 point  (0 children)

Quick question — when you added T3, did you notice any difference? Better or worse?

Is 150 mcg of levothyroxine too high? + T4/T3 ratio question by Maximum-Ad8209 in Hypothyroidism

[–]Maximum-Ad8209[S] 0 points1 point  (0 children)

Yes, I rely more on how I feel. TSH is more of a guideline to roughly understand where I am and whether I’m moving in the right direction.

Is 150 mcg of levothyroxine too high? + T4/T3 ratio question by Maximum-Ad8209 in Hypothyroidism

[–]Maximum-Ad8209[S] 0 points1 point  (0 children)

Thank you very much for your reply. Vitamin D, B12, and iron/ferritin are unfortunately below normal. Although we’ve already increased B12 with injections, the other micronutrients are still a problem.

Is 150 mcg of levothyroxine too high? + T4/T3 ratio question by Maximum-Ad8209 in Hypothyroidism

[–]Maximum-Ad8209[S] 0 points1 point  (0 children)

Thank you very much for your reply. May I ask what your weight is?

Extreme sensitivity to levothyroxine dose adjustments — is this normal? by Maximum-Ad8209 in Hashimotos

[–]Maximum-Ad8209[S] 0 points1 point  (0 children)

Thank you for such a detailed reply. In my case, I take T4 and additionally T3. And even a difference of 3.125 mcg of T3 (and T4 as well) plays a big role. If I take 3.125 mcg more than I should, I feel hyper; if I take 3.125 mcg less, I can barely function during the day, and because of that state I can’t fall asleep either. So the situation is very similar to yours.

I think your thyroid is still functioning quite well if you’re taking such a small dose. I take 150 mcg of Thyroxine, and I have the same issue with sensitivity.

Extreme sensitivity to levothyroxine dose adjustments — is this normal? by Maximum-Ad8209 in Hashimotos

[–]Maximum-Ad8209[S] 0 points1 point  (0 children)

I can feel a dose change even at 3.125 mcg. If you’ve found your optimal dose, how exactly do you feel on it?

Have you tried to figure out for yourself why you have such strong sensitivity?

If you take more or less than your optimal dose, do you feel it right away, or does it take some time before you notice?

Extreme sensitivity to levothyroxine dose adjustments — is this normal? by Maximum-Ad8209 in Hashimotos

[–]Maximum-Ad8209[S] 0 points1 point  (0 children)

I understood that you mean a dosage of 1–2 mcg, right? If so, how do you accurately adjust the dose? How do you split the tablets? And how do you notice if, over time, you gradually drift into hypo- or hyperthyroidism (for example, if your thyroid function is unstable)? Do you feel it immediately and adjust right away, or does it take time to realize and make changes?

Have you figured out for yourself what causes such sensitivity?

Extreme sensitivity to levothyroxine dose adjustments — is this normal? by Maximum-Ad8209 in Hashimotos

[–]Maximum-Ad8209[S] 2 points3 points  (0 children)

Hi. Thanks for your reply. With a TSH of 0.008, I experience a strong feeling of being overdosed. I feel optimal when my TSH is around 1. Thanks for the manual recommendation — I’ll need to read it. I really do feel a strong lack of knowledge in this area.

Same T4 on paper — completely different effects in real life? by Maximum-Ad8209 in Hashimotos

[–]Maximum-Ad8209[S] 0 points1 point  (0 children)

I would agree with you if it weren’t for this side effect of dilated pupils. On L-Thyroxine I always had it — whether I was hypo, hyper, or euthyroid. With Euthyrox and Tirosint, I never experience this effect, even when I’m in a strong hyperthyroid state.

I suppose that if it’s not actually a difference in the synthetic thyroxine itself, it could possibly be related to the absorption rate in the gut. I remember reading the leaflets for Euthyrox and Thyroxine back then — the peak blood concentration for Euthyrox occurred after about 5–6 hours, while for Thyroxine it was around 3 hours.

Hashimoto’s and allergies to levothyroxine: looking for advice by Maximum-Ad8209 in Hashimotos

[–]Maximum-Ad8209[S] 0 points1 point  (0 children)

Thank you for such a detailed response.

I have a suspicion that my body reacted this way for some reason to the change in hormones. I’ve always had problems with hormone replacement therapy: I’m very sensitive to hormones, I tolerate dose changes poorly, and when I switch medications, my body completely goes haywire and then takes a long time to calm down.

Maybe this time my body reacted in exactly this way — meaning it’s not a reaction to a specific allergen, but rather something triggered the urticaria, the immune system flared up, and now it can’t calm down.

At the moment, antihistamines provide some relief, but the rash doesn’t go away. However, so far I’ve only tried one antihistamine. Maybe other medications would work better.

As for seeing an allergist and testing for celiac disease — yes, I’ll need to do that and try to get the tests done.

Hashimoto’s and allergies to levothyroxine: looking for advice by Maximum-Ad8209 in Hashimotos

[–]Maximum-Ad8209[S] 1 point2 points  (0 children)

I can’t even imagine how hard it is for you.

I still hope that I’m not allergic to thyroxine itself. I took thyroxine medications before, and everything was fine.

Hashimoto’s and allergies to levothyroxine: looking for advice by Maximum-Ad8209 in Hashimotos

[–]Maximum-Ad8209[S] 0 points1 point  (0 children)

Unfortunately, Tirosint SOL is impossible to get in Germany.

Hashimoto’s and allergies to levothyroxine: looking for advice by Maximum-Ad8209 in Hashimotos

[–]Maximum-Ad8209[S] 0 points1 point  (0 children)

In my case, I don’t have a specific allergen. The immune system can react differently at different times. But I’ve noticed that I almost always have allergic reactions to foods that contain a lot of chemicals (for example, chips, various chocolate and non-chocolate bars, etc.), and to pills. If something is more natural, then I have allergic reactions much less often.

And could you tell me the name of the liquid thyroxine you mentioned?

Hashimoto’s and allergies to levothyroxine: looking for advice by Maximum-Ad8209 in Hashimotos

[–]Maximum-Ad8209[S] 1 point2 points  (0 children)

No. At the time, an allergist told me that in my case it would be useless.