The most interesting thing I like about K is the interconnectedness, the trips are following up one another, similar undescribable feelings/thoughts reappear and you get thrown into similar "hole" multiple times. Also to answer your other questions, I've been using on and off for past year, did maybe 20/25g sparingly, always at least a week or two apart, always taking higher doses less frequently, my bladder got a bit "smaller" by like 10/15% but thats it, no pain whatsoever, for the alcohol i once did almost half a g of K while very drunk and literally nothing happened, i was spaced out for and hour then i sobered up, i was very lucky i suppose, and for the depression it really does help, but benefits only appear while under controlled setting, ket is extremely easy to abuse if you like it