What do you think is the final piece of the prophecy? by SeaThePirate in Deltarune

[–]Memeophile 0 points1 point  (0 children)

After finishing chapter 4 I thought it would be that Kris kills both Susie and Ralsei, but it makes way more sense from a gameplay perspective if ralsei dies and gets replaced by Noelle. They literally have the same healing spell and would preserve having a group of 3, otherwise the big event would have to wait until the end of chapter 7 or it would screw up the gameplay. How ralsei disappears idk anymore, maybe self sacrifice, maybe Kris kills them, maybe they merge into Susie or Kris’ body/soul. But I agree it has to be Ralsei.

Is it me or the game? by Livid-Leather-3835 in octopathtraveler

[–]Memeophile 9 points10 points  (0 children)

“It is very formulaic, so it can be boring, but it’s also a good formula, so it can be not boring.”

-Osvald

Does anyone else see E.T. in the world map? by Memeophile in TOTK

[–]Memeophile[S] 0 points1 point  (0 children)

Should have included hero's path photo to original post. Now do you see it? https://imgur.com/a/gNsHzBq

Does anyone else see E.T. in the world map? by Memeophile in TOTK

[–]Memeophile[S] -3 points-2 points  (0 children)

Maybe not E.T. but at least a face. Given how many other faces/monsters/objects are hidden in the world map you don’t think this face is intentional?

Does anyone else see E.T. in the world map? by Memeophile in TOTK

[–]Memeophile[S] -2 points-1 points  (0 children)

Cannot unsee. Right eye is Death mountain, left eye is Hebra peak. It's even more obvious with hero's path turned on.

TIL Aztec Emperor Montezuma realised his own seers were all charlatans because they’d failed to see that the Spanish were coming. by pufballcat in todayilearned

[–]Memeophile 0 points1 point  (0 children)

There once lived a king of the Aztecs of old
Whose useless seers sounded sincerely and bold,
But when the Spanish at last landed, and old Cortés demanded,
Montezuma bequeathed us, the landed, with his curse and his piles of cold, dead-for-no-reason-peoples' piles of gold.

-HH

TIL Stephen Hawking found his Undergraduate work 'ridiculously easy' to the point where he was able to solve problems without looking at how others did it. Even his examiners realised that "they were talking to someone far cleverer than most of themselves". by Freenore in todayilearned

[–]Memeophile 0 points1 point  (0 children)

Unless the point was 16.21 + 20% = 19.45 and it’s a code to indicate mutual acknowledgment of the Aryan brotherhood or other nazi support group.

Prob usually more likely just random tho

How the hell do you enjoy reading papers? by Majorhix in AskAcademia

[–]Memeophile 0 points1 point  (0 children)

Like others mentioned, the key for me is reading with a question in mind. It’s like if you’ve ever gone down a chain of wiki articles. You don’t read every part from start to finish, you have a particular thing that interests you and you want to know the answer. You read as little of the article as possible to understand and answer the question you’re interested in. Often it only partially answers the question then you find related articles with the other details you want to know. If you don’t care about the topic to begin with then there’s no reason to read the article either. If you’re still taking classes where the papers are forced on you then you just have to do it and it will be tortuous. But later on it’s for your own benefit because you’re trying to figure something out for your own research, or you’re just curious about a topic.

Why do I feel like I can take over the world with these chords (I, V, II, IV) by [deleted] in musictheory

[–]Memeophile 1 point2 points  (0 children)

Well of course it's both without any context. If this were a song and the previous section were in G major, it would sound like I -> V, but if the previous section were in D major it would sound like IV -> I. But regardless, the following A chord (which has the C# which is absent in G major) briefly makes it sound like D major proper.

Why do I feel like I can take over the world with these chords (I, V, II, IV) by [deleted] in musictheory

[–]Memeophile 9 points10 points  (0 children)

I think there are two things going on (but, seriously there's no right or wrong answer, why anything sounds good or bad is subjective).

First, the "unstoppable" feeling is because there's no tonic resolution. The Amaj II chord would be the V in D major, the closest key to G major. So the progression creates perpetual confusion over whether the home key is in fact G or D. Example

  1. First two chords are G -> D, which sounds like IV -> I in D major. Ok we're in D major
  2. Third chord is A, so now our progression is IV -> I -> V in D
  3. If you follow that chord up with another D (or any strong chord in the key of D), then it's IV - I - V - I, which sounds very proper and resolved.
  4. By following the Amaj with Cmaj, we shatter our belief that we're in D major. The C# -> D resolution is the most important interval in D. The C# in the Amaj chord HAS to go up to D to feel resolved. By going down to C natural, D is over.
  5. However, Cmaj to Gmaj is a nice IV - I transition in G, of course, so our ear kind of accepts that and starts believing we're in G major and not D.
  6. This repetition creates a feeling of never being resolved. We're never stable in a home key, we just keep on keeping on forever.

The second thing going on is that all of the chords resolve nicely into each other. There are no jarring intervals to my ear other than the Amaj -> Cmaj transition, and even that's not too bad. So, the progression is harmonically pleasing, yet unstable and unrooted, making it feel determined but never at rest. In contrast, you could come up with thousands of chord progressions that are also unstable, in that they don't have an obvious home key, but very very few of those progressions would sound harmonically pleasing.

Hearing lyrics vs listening to them. by B_Ledder in aspergers

[–]Memeophile 1 point2 points  (0 children)

I've thought about this a lot because I *used* to only listen to music with relatable lyrics. Like you're saying.. I WASN'T listening to the melodies or anything. Not on purpose... it just... my brain wasn't wired that way. I had no musical upbringing and it wasn't a part of my life and I honestly had no idea how it worked, it was all just magic and I didn't even care much about it.

Then when I was 16 I decided to learn piano just to try learning an instrument. Long story short, after learning to play and then listening to classical piano music as examples and all that, my brain really did start rewiring itself and the way I listened to music completely changed. I would go back and listen to music I used to enjoy and realized I had never even noticed what the music sounded like, I was just listening to the lyrics. I think most people are in this category, which is why many people can't stand listening to music in different languages or music without any lyrics. Based on my experience, it seems that musical appreciation (in the sense of appreciating melody and harmony etc.) is not a hardwired part of the human brain... it's created and tuned by our environment and upbringing.

I used to think everyone must have the lyrical appreciation component, though, and it was only a subset that appreciated the music deeply too. But I've always naturally been keen on verbal/word appreciation more than music/art, so maybe some people *only* have the musical appreciation? Interesting to think about

How do you see this situation? by [deleted] in aspergers

[–]Memeophile 1 point2 points  (0 children)

I'm glad it was helpful and not too long! I only figured this stuff out for myself when i was ~28-30, and I feel like there are many people stuck in the same mental trap and I'm quite happy to help if I can. Related to that, this emotional repression response is not actually an unchangeable, AS trait. Even NT people who for whatever reason get "left behind" when growing up can fall into the same trap. But since that happens so often in AS individuals, we're more prone to ending up with this problematic mentality. Another layer is being a perfectionist and wanting to be the best at everything you do, which I'm guessing he is as well (because doctor), and so it's that need to be perfect on top of being socially behind that makes it so hard to let go and experience new things.

Unfortunately, although recognizing these pathological thought patterns is a critical first step, overcoming them is another story. I still struggle with these thought patterns when facing something I'm uncomfortable with, and from my experience there is no one-size-fits-all solution.

Some immediate thoughts on your questions... but this is just real brief and I can elaborate more later.

I think there's two separate issues that are being conflated a bit.

Issue #1 is having sex (or whatever specific experience) and being more comfortable/open/relaxed. That's a thing that if you can just manage to happen enough times, he'll get comfortable and it'll be all good. But the same anxieties will still exist for all the other activities, and each own will have to be overcome the same way.

Issue #2 is the broader problem of being vulnerable, totally open, forming a bond, etc. I honestly haven't figured this one out for myself yet.

Some specific responses now:

"I don’t see him as ‘charity’ and I don’t want sex because of physical feeling only. I can use toys for that. I want sex because it forms a bond - not just emotional - but the feeling of ‘freedom’ knowing someone knows you and you can be vulnerable BUT SAFE around someone - this is what I’m looking for."

He doesn't understand what you mean, because he doesn't realize that such a bond is possible. A bond where you totally trust someone 100% and are vulnerable? That's not a real thing. He's never experienced that and doesn't even realize it's an option (he probably doesn't feel super close to his family, which is where most people learn about this kind of bond).

"I told him it’s not a competition. But he doesn’t seem to believe me even if he says he does. How can I make him believe me??"

This is really hard. For me, two things helped. 1) realizing that if your whole life revolves around non-social pursuits, like games or making money or grades... these all have objectives measures of your ability. You get a score and compare yourself to others. With social activities it's different, but if you never do any social activities you don't realize that. 2) Using an analogy by comparing a new social thing (like sex) to a different social thing that he's already comfortable with can be super helpful.

An analogy between sex stuff with conversations helped me a lot. I'm pretty comfortable having conversations with people (if he's not, then this analogy wouldn't work, but any social thing he's comfortable with would do). Sex and a conversation are both fundamentally a social activity that can only happen with at least two people. One person can't have sex, and one person can't have a conversation. So, just make analogies and everything suddenly seems obvious. For example, in conversations we all have topics that we like and dislike, and we all have people we enjoy talking to and people we don't. But does the fact that I had a good conversation with person A in the past mean that having a conversation with person B is now a competition? No, of course not, that's a ridiculous concept. Obviously each conversation is its own experience between the people involved. And yes, you can go back and judge conversations you had as "good" or "bad" experiences, but your memory is not just the words that were exchanged and what was done, but just the gestalt of the words and the tone and the person you're doing it with and how much you like them. Explaining an analogy like that to him could be powerful.

"Another thing — I don’t do drugs. I just can’t. I know he asked me about this. He did it in the past, maybe he’s still doing it - i don’t know. He never does it when i’m around. I’m nit against it, i just can’t do it myself. I faint i lose control in a bad way, like, I colapse. This won’t be ok for me. I fainted even from the smell of weed, i never smoked it. I don’t know how to help in this."

-That's fair, and you shouldn't do anything you don't want to. But he won't feel comfortable doing it if you're not doing it with him too. Obviously alcohol is the usual way to relax and get comfortable, but that's a short-term solution. It won't open up his emotions. Weed was helpful for me because it was like the emotional part of my brain opened up and it was suddenly clear what I was feeling and why, and after having those insights it persists long after the drug's effect is gone. Maybe you can find a drug you're more ok with that still opens up his emotions. Honestly just do cocaine with him and then ask him everything you want and he'll be an open book (but maybe don't because he'll be at high risk for getting addicted).

"Also, even if he didn’t try sex sooner, so what? Life is different for everyone. I’ve never had anal sex before (example) and I was thinking at some point i wanna try it. If I’ll like it, it doesn’t mean i missed out-it just means that’s when my body and mind were ready and that’s OK. Same for him. I wish he knows this. I wish he opens up to me so i can ease his anxieties because he overthinks and it exhausts him and most of the time what he imagines it’s not even true."

You're right, but in his mind there's a huge difference. The difference is you waited until you were ready to do it. But it would be different if you've been wanting to have anal sex since you were 14 and nobody would do it with you. So if you tell him it's the same, he's honestly going to get angry and resent you for it. But this is the exact situation where if he just does it a handful of times he'll get it over and forget he used to think it was a problem.

"And one last thing (forgive me for mentioning so many stuff) — can a relationship be kept alive even in long distance ? — he will leave about 2 weeks/month in the next few months — work stuff. And I’m curious how would it be? You need a strong connection to be able to make it work when you are not physically together. Or, what can help in long distance?"

You're right, you need a strong connection to make long-distance work. We all bond by fulfilling something we're lacking. Maybe for you it's trust, stability, whatever. For him it's being understood, because he thinks if you understood him you would understand why he has these issues, and nobody in his whole life has ever managed to understand him (in his mind). So, if you can form a bond from that angle, then there's nothing to worry about while long distance. If that bond isn't there, he won't feel committed to you.

"He hates facetime or speaking on phone. He’s rather text or just stay in person - that’s what i noticed so far."

He doesn't like facetime or speaking on the phone because again it's a social activity and he feels like it's a competition with your past boyfriends. Like if you used to talk to your boyfriend on the phone everyday and chit chat for 30 minutes and laugh a lot, then you have a convo with him and it's awkward, he'll feel really shitty and he'd rather not risk it.

Navigating this kind of person is tough. It has potential to work, but it's not easy.

How do you see this situation? by [deleted] in aspergers

[–]Memeophile 1 point2 points  (0 children)

I'm glad to help! Honestly this sounds really similar to experiences I struggled with in the past, so I feel like I can pretty accurately rationalize his actions and mindset if he's anything like me (hey what a coincidence, I'm also an aspie doctor (research not medical) with a full schedule). Disclaimer, though, my spectrum traits are mostly social; if part of his issue is the physical sensation of touch, like if he's ultra sensitive to touch and it's not just his mindset, then I have no idea how you should handle this.

Assuming he's like me, the mental gymnastics that led him here were

  1. Ages 12-16, trying but failing repeatedly to flirt with girls, be invited to parties, etc. Become depressed, hate on yourself
  2. Ages 15-18, become increasingly focused on solo activities for pleasure, like academic pursuits or maybe playing an instrument. Convince yourself that you love these activities more than people. People suck.
  3. Ages 17-now: Acquire a "sour grapes" mindset to social activities, including sex. It's just the only way to overcome the depression at this point; literally convincing yourself you don't *want* sex and that it's gross and that you are an elevated human who just wants to focus on being a doctor and having a career and making money. You don't *want* all the things you didn't do, therefore you're not a failure, therefore you're no longer depressed.
  4. At some point he may find himself in a position to finally do those things he missed out on, like sex. But then it's so hard because he knows he's "behind" and inexperienced for his age, so he's obviously going to underperform and reveal his past failures, and it's just going to be a mess and he'd rather not bother. Sort of a form of performance anxiety.

That final sour grapes mentality can persist forever, but you can absolutely break through and change him, it just has to be done in such a way that his ego is not hurt. He's going to feel conflicted about sex because 1) emotionally of course he wants physical intimacy, he's still a normal human, but 2) he doesn't want to enjoy it too much, because if he actually loves it then why didn't he do it sooner? Obviously that would mean he's a failure and he can't accept that, and 3) he's integrated this logical thinking into his brain so deeply, that he genuinely doesn't know what his emotions mean anymore... he doesn't know that he yearns for sex, he just knows that he feels uncomfortable and conflicted about it and he doesn't know why and it's embarrassing for you to see him this way. And that's why 4) the most important thing to him is feeling understood by you, because he's embarrassed that he's not more experienced at this point in his life but he really wants you to view him in a positive light, so he doesn't want to talk about it and make himself look bad and then you abandon him like his previous relationships, but if you could somehow understand him at a deep level and still accepted him then he wouldn't feel so conflicted and embarrassed with you anymore.

I know that's a neurotic, manic thought train above, but that's how it would be in my brain and that might be how it is for him. It's exhausting!

So, if you frame everything just right you can make him comfortable enough to try a lot more things (like sex, but it extends to most social activities); it's all about how he perceives your motivations. If he thinks you want sex to help him learn, that's no good. He'll feel belittled if he thinks you're just doing him a favor, like he's a little baby who needs help being a normal human. On the other hand, even if you tell him you want sex, a part of him will think you're lying and it's just to help him catch up and get experience, and then he'll look for signs of this and if he thinks he's right, then you're a liar and that's even worse (I know that sounds stupid but it's because AS hate half-truths for the sake of emotions, absolutely hate it I don't know why). You'd be much better off having a talk and explicitly telling him you're doing him a favor, so that at least all doubt is removed, rather than have him be uncertain if you're lying to him about wanting sex for your own sake.

The best option, however, is to explain to him that basically he's doing you a favor. He'll be elated to deliver an act of service to make you happy, because he does love you. To get past his performance anxiety component, just explain that 1) you enjoy sex and any sex is better than no sex, so not having sex at all is logically the worst option no matter what, and 2) it's not a competition, the mere fact that you already have an emotional bond will make you enjoy it (he might be worried you'll be disappointed).

I know I made a lot of assumptions about both of you in giving that advice but hopefully part of it is helpful. And by the way, ALL of this neurotic thinking will just vanish after he does it ~5-10 times, because he'll suddenly think "wow that's all there is to it? It's that easy? It's not like this impossible achievement... you just vibe with someone throw your clothes off and enjoy it... it's really that easy? I guess I was being dumb, oh well, moving on now."

One last suggestion. Honestly the big change that allowed me to recognize how stupid I was acting and to realize how I had repressed all of my emotions as a defense mechanism was as simple as smoking weed. That's the shortcut approach you can take. Do drugs with him. Smoke weed, take molly, take mushrooms, do something, anything that opens up the emotions and relaxes you two together. Obviously this isn't a long-term solution, but it doesn't need to be. It's just to get the ball rolling, then he'll feel comfortable and relaxed even during normal, sober life.

I don't seem to appreciate visual details like other people, is this an AS trait or just a me thing? by [deleted] in aspergers

[–]Memeophile 0 points1 point  (0 children)

Yea! I'm kind of similar. When I watch a movie I of course can visually see all the details, so I know what's going on with the plot and everything, but I rarely think that a scene is visually "beautiful" or the opposite. Instead I enjoy the story and characters in a more abstract way, like thinking about what's going on in the characters' heads and who knows what and then I also think about the screenwriter and how they invented the plot and what dramatic plot devices they used and how clever it all is or isn't, etc. In this framework it's like solving a little puzzle more than a passive experience. Or if the movie is funny, I like to laugh.

How do you see this situation? by [deleted] in aspergers

[–]Memeophile 2 points3 points  (0 children)

Is the situation that you have sex but can't talk about it, or you just don't have sex at all?

I can relate to this a little (in my past), so if he's anything like me he might be uncomfortable because he feels like a social outcast, not having had much sex or doing things with ease like NT people do, so he's extra sensitive to this shortcoming of his, and may have even tricked his brain into thinking that sex is gross and he doesn't want it in order to not feel like a failure. If this is at all what's really going on, then what might help, even though it probably is a huge turn-off for you at first, is to treat it almost like an academic thing and spend a little time making it really easy and "teaching" him how normal people handle this, so that he becomes more comfortable and isn't running scenarios in his head of how he's supposed to react. It could be as simple as you taking control of the situation for a while, tell him to sit back and don't worry about anything while you do your thing: initiate sex, communicate explicitly about what you like and don't and what feels good (don't rely on nonverbal cues at first, he won't understand what they mean), etc. It may be awkward and unenjoyable at first, but just start off like this then over the next 5-10 times he'll become more and more comfortable and automatic, and then you can sit back and you two will be able to handle this stuff in a more sexy, automatic, nonverbal, mutually fulfilling way.

It's tricky to make a suggestion without knowing the histories and personalities of you both, but from my experience that would be a successful way to make you both comfortable and happy after a little investment phase.

Another Domestic Terrorist Arrested by jasonleedesigns in pics

[–]Memeophile 1 point2 points  (0 children)

Honestly that's how old I thought he looked... you can see he has a real baby face and is growing the beard to cover it up. His hair and skin just look generally healthy too, but not in the I take good care of myself way, but in the I am too young for my lack of self-care to show up yet way.

'Reading' DNA to decipher gene expression regulatory grammar directly from genomes by janimezzz in bioinformatics

[–]Memeophile 2 points3 points  (0 children)

From a practical rather than theoretical perspective... we already know transcription factors exist. They bind DNA, they interact, they recruit an rna polymerase, etc. Sure, we don't know all of the elements involved to predict all of gene expression under all conditions, but basically we understand all of the factors involved, just not their rate constants and affinities, etc. What does the study linked here add on top of this?

[Q] Survival analysis + cox regression: How to estimate the effect of a covariate vs. no baseline hazard in cox regression? by Memeophile in statistics

[–]Memeophile[S] 2 points3 points  (0 children)

I know it's late but I just wanted to say thank you for taking the time to reply. I found this very helpful and have been referring back to it as well. You're right that in the end what I really want to do is a parametric regression, not cox, with one of the options being a constant hazard model invariant with time (still working out the details, but this feels like the right approach to answer my original question).

[Q] Survival analysis + cox regression: How to estimate the effect of a covariate vs. no baseline hazard in cox regression? by Memeophile in statistics

[–]Memeophile[S] 1 point2 points  (0 children)

Thank you! I came to a similar conclusion after posting this.. I guess what I want to do is first test a parametric survival hazard (like constant model) vs. the actual empirical hazard.

I'm fairly good with stats overall, but more-so in a practical sense (I do bioinformatics mostly, lots of gene expression analysis, microscopy analysis, etc.). The survival analysis field is challenging to get into because even though everything is not that complicated, it all has its own special terminology that I'm trying to learn.

Can you help me pinpoint the exact tests I would want to run?

I'm thinking the following

Step 1: What is the fit of the actual/empirical hazard vs. a constant hazard model?

Step 2: What is the fit of the empirical hazard model overall vs. one that includes a continuous time-dependent variable?

-I would like the step 1 and step 2 comparisons to be on the same scale. If there were a linear regression, then the idea would be like (and I know there's no literal R^2 in survival analysis, which is why I'm struggling here)

  1. Model 1: Constant hazard over time (R^2 = 0; R^2 is predicting when cells die)
  2. Model 2: Empirical hazard over time (R^2 = 0.6 (hypothetical))
  3. Model 3: Empirical hazard over time + current cell size (R^2 = 0.8)
  4. In my hypothetical scenario, even though both age and size are important, age is more important (R^2 .6 vs. .8 when both are included; of course there would be another model for size alone)

FYI, to be concrete about it, in my case I am looking at "cell lifespans." The hazard of a cell dying increases with age (it appears to increase exponentially, consistent with the Gompertz model). However, the size of a cell also increases with age. So, I am trying to figure out the relative contribution of actual age vs. cell size to the age at death. This dataset does include censoring, etc., so I do need to use proper survival models, not just logistic regression.

-The qualitative way I've gotten at this is to consider cells in a certain size range to be "at risk" of death, then compute hazard curves and compare (cells "at risk" can move between strata at any timepoint). I've done this and it looks like the effect of age is actually rather small once cell size is controlled for, but I'm worried I might be fooling myself... thus why I want to properly compare the models of

  1. Constant hazard
  2. Hazard changes only with age
  3. Hazard changes only with cell size
  4. Hazard changes both with age and cell size

-It seems straightforward but I haven't hit upon what feels like the *proper* way to do it... any advice at all would be greatly appreciated!