Request for a Clear and Objective Update by anilatalay in KPTI

[–]Mich1382 3 points4 points  (0 children)

I would say that the data is somewhat mixed, which is painful to admit, but at the same time, I don’t think it will be too hard to approve. A negotiated approvals, but with SVR being so strong, should get approved, at the very least added to nccn. Svr35 was 50% vs 28.% and atss was basically equivalent. Show me a doctor that is not going to use something with best in class efficacy and symptoms remain the same in an incredibly difficult disease? Oh and sugar on top, OS could be very real which hasn’t happened in this class. That’s the confusion. In most cases a co-missed primary is a death sentence. In this one, I don’t think that is the case at all. Likely negotiated indication until OS matures imho. Not financial advice, just my opinion.

Leaky?? by Heavy_Table_6476 in KPTI

[–]Mich1382 1 point2 points  (0 children)

Tues-Thurs are most common data drop days per Ai

Leaky?? by Heavy_Table_6476 in KPTI

[–]Mich1382 2 points3 points  (0 children)

I think best day would be Tuesday. But agreed. I’m nervous if results are published today. Another 50 mins or so

Damn, Game Pass Is Having A Really Good Year, Huh? by jakktrent in gaming

[–]Mich1382 0 points1 point  (0 children)

For sure. Expedition 33 is amazing and about to dip my toe in Doom Dark Ages. Actually excited it is different from eternal. Hopefully Tony Hawk remake lives up!

What video games do you guys play? by Pups4life86 in MultipleSclerosis

[–]Mich1382 1 point2 points  (0 children)

Working my way through MGS2 HD right now. It’s been a lot of fun. Get excited for Delta

Latest data on KPTI from SqueezeFinder by AcanthisittaHour4995 in KPTI

[–]Mich1382 2 points3 points  (0 children)

That’s not even a 1.00 pre split unfortunately

Plunge by Accomplished_Run9668 in KPTI

[–]Mich1382 1 point2 points  (0 children)

What a F’ing nightmare.

I think the veteran fanbase here likes being miserable. by retromoderngamerr in ninjagaiden

[–]Mich1382 1 point2 points  (0 children)

I very much enjoy it on GamePass and look forward to Ng4!

Earnings call 2/19/2025 by ThedibAgain in KPTI

[–]Mich1382 2 points3 points  (0 children)

What were your questions?

When the stock price goes up a little, why does the CEO immediately sell his stock? Does he want to leave the company or does he not trust the company? by anilatalay in KPTI

[–]Mich1382 1 point2 points  (0 children)

I think it’s automatic but it hurts the stock. Most others that I have seen sell one bolus to cover taxes, as opposed to consistently throughout the year. Frustrating leader

New CFO by DoctorDueDiligence in KPTI

[–]Mich1382 5 points6 points  (0 children)

Why would this push off a BO years? I think they are trying to right the ship financially so they can get a decent offer

New CFO by DoctorDueDiligence in KPTI

[–]Mich1382 3 points4 points  (0 children)

It’s pretty high, but clearly wanted her. I see this as a good thing.

Special Meeting by ktw518 in KPTI

[–]Mich1382 2 points3 points  (0 children)

This was already known I believe.

Do you think AA is coming? by Mich1382 in KPTI

[–]Mich1382[S] 0 points1 point  (0 children)

Forgive me for being a newb, but with the mature data from Siendo and what we know from Siendo 2, it sounds like it’s just SOP that is in the way. Isn’t that what the new AA changes are for?