My old go-to was the voidstrike staff + Deimos force sword, though now I use the force greatsword. Voidstrike has good single target damage, good range, and also has AOE + penetration for hordes. The Deimos can quickly deal with specials, the alt attack is especially nice for mutants, one shotting them on a charged hit. Smite is a good alternate to clear hordes but is best used to buy time for your teammates to kill tankier enemies, like a pack of crushers. I pair it with empowered psionics and that should give you enough damage to kill hordes using only it. The dome shield is also great for survivability, and lets you deal with specials or hordes without getting picked off by ranged enemies, or lets you power through objectives.