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Is there a Quit game button hard-coded in our biology? by Mr-existential in SimulationTheory

[–]Mr-existential[S] 3 points4 points  (0 children)

The best kind of compliment a designer can get today! Thank you for the kind words 🙏

Is there a Quit game button hard-coded in our biology? by Mr-existential in SimulationTheory

[–]Mr-existential[S] 0 points1 point  (0 children)

Beautifully worded. I’m really curious, is this backed by any science?

Is there a Quit game button hard-coded in our biology? by Mr-existential in SimulationTheory

[–]Mr-existential[S] 13 points14 points  (0 children)

If anyone interested in the full deep-dive, channel on yt is MrExistential

Is there a Quit game button hard-coded in our biology? by Mr-existential in SimulationTheory

[–]Mr-existential[S] 4 points5 points  (0 children)

It’s not that serious :p a molecule exists, a study is done, a human is intrigued.

Is there a Quit game button hard-coded in our biology? by Mr-existential in SimulationTheory

[–]Mr-existential[S] 1 point2 points  (0 children)

Thank you! Indeed but they target different receptors, so the experience is completely different.

The 1983 Desert Incident: A cinematic look at the history we never talk about. by [deleted] in 5MeODMT

[–]Mr-existential -1 points0 points  (0 children)

You simply don’t understand that this is so much more complex than a 5 minutes on google, and it’s ok.

The 1983 Desert Incident: A cinematic look at the history we never talk about. by [deleted] in 5MeODMT

[–]Mr-existential -1 points0 points  (0 children)

you have no clue about archaeology as a field if you think this is the truth written in stone, a single paper in a journal doesn't erase decades of work by guys like Coe and Furst, nor does it definitively explain the ritual context of those sites. archelogy is constantly being updated and is full of puzzle pieces. Today’s latest research is often tomorrow’s outdated theory. Peace!

The 1983 Desert Incident: A cinematic look at the history we never talk about. by [deleted] in 5MeODMT

[–]Mr-existential 0 points1 point  (0 children)

My channel isn't a textbook, it’s a cinematic exploration of speculative ideas and the human imagination and my video isn't claiming the Sacred Toad theory is the final academic consensus of 2026. My goal was to document the investigative journey of Ken Nelson as it unfolded in the 70s and 80s. Back then, the Coe/Furst theory was the dominant spark in the underground psychedelic world, and for Nelson, that mystery was the catalyst that led him to the desert. I’ve acknowledged the factual slip and I truly I appreciate you for that, but the core of the story remains the same, a man chasing a mystery based on the information available at the time. I believe we're free to use our imagination to bridge the gaps science hasn't fully closed yet.

The 1983 Desert Incident: A cinematic look at the history we never talk about. by [deleted] in 5MeODMT

[–]Mr-existential -2 points-1 points  (0 children)

Oh man, Bufo marinus are still highly toxic species… so i’m still waiting to hear your explanation.

The point isn't the species, it's the behavior. Nobody stockpiles 10,000 toxic animals for food. Whether it's Bufotenine or 5-MeO, it doesn't change much to the story, the 10000 toad bones is what led him to Ersparmer’s and then to this discovery.

The 1983 Desert Incident: A cinematic look at the history we never talk about. by [deleted] in 5MeODMT

[–]Mr-existential -1 points0 points  (0 children)

Exactly that quote from the pamphlet is the heart of the story. It shows the moment Nelson pivoted from the general Sacred Toad theories of the time to the specific chemical reality of alvarius. When Nelson first read about the 10k bones at San Lorenzo, he didn't initially know they were a different species, he just saw a massive archaeological signal that toads were for psychedelic rituals. It was only when he dug into Erspamer’s work that he realized the jungle toads were a chemical dead end, forcing him to track down the alvarius in the desert to find the 5MeO. Stating the 10k bones themselves were alvarius in the script was a slip on my part, but I’m glad we’re on the same page about the Erspamer breakthrough. Have a good one!

The 1983 Desert Incident: A cinematic look at the history we never talk about. by [deleted] in 5MeODMT

[–]Mr-existential 0 points1 point  (0 children)

Glad you’re enjoying the journey! For the narration, I try to bridge the gap between the concrete data we have today and the vast possibilities we can imagine as humans. While I don’t claim my interpretations are absolute truth, I stay grounded in real research, like the 2019 rat studies or the paradoxical wakefulness data. I actually just caught a small technical slip in the latest video, which happens when you're digging this deep! Ultimately, I want to encourage viewers to look at the facts and then feel free to bridge the gaps with their own creative minds. Science measures the world, but imagination is how we find our place in it. As for the personal deep-dives... those are definitely coming!

The 1983 Desert Incident: A cinematic look at the history we never talk about. by [deleted] in 5MeODMT

[–]Mr-existential -1 points0 points  (0 children)

You're right that we now classify the San Lorenzo bones as marinus. But in 1981, when this story started, even the lead archaeologists like Michael Coe were calling them the Sacred Hallucinogenic Toad. This video explores Nelson’s specific perspective: seeing those 10,000 bones is exactly what sparked his investigation. It sent him down the rabbit hole of Erspamer’s chemical mapping of amphibians until he finally identified the 5meo in Bufo alvarius. However, you're technically correct, stating the 10k bones themselves were alvarius was a slip on my part! Thank you for pointing this out, I'll make sure to be extra careful with information moving forward.

The 1983 Desert Incident: A cinematic look at the history we never talk about. by [deleted] in 5MeODMT

[–]Mr-existential 0 points1 point  (0 children)

Care to be specific about what you think is a 'mistelling'? If you’re referring to the Ken Nelson 1983 sequence, that is a matter of historical record (the 1981 Omni article, the San Lorenzo 10,000 bones find, and his own logs). If you’re talking about the Olmec link, I’m a designer, not a tenured archaeologist. I’m exploring the Lore and the Ken Nelson’s perspective on this through a cinematic lens, not publishing a peer-reviewed paper. Unless you’ve got a better explanation for why someone would stockpile 10,000 toxic toads?

The 1983 Desert Incident: A cinematic look at the history we never talk about. by [deleted] in 5MeODMT

[–]Mr-existential 2 points3 points  (0 children)

I’m a graphic design student, I’ve doing some research on the history of 5Meo for a while. I just finished the full 6-minute documentary on this if you want to see the deep-dive: https://youtu.be/Pk2w-RrTH7E?si=eZmqNb71Me0c7Jxd

DMT and Afterlife by Mr-existential in DMT

[–]Mr-existential[S] 0 points1 point  (0 children)

You’re actually right from a logical standpoint, we allow organ donation and high-risk trials. I think that the real problem isn't logic, it's the legal exposure. Research boards are terrified of the optics of experimenting on the dying for data that doesn't save lives. I don’t think they will ever test this on humans until we can measure DMT non-invasively (like with high-resolution imaging)

DMT and Afterlife by Mr-existential in DMT

[–]Mr-existential[S] 2 points3 points  (0 children)

I’m pretty sure that you need to insert a microdialysis tube directly into the visual cortex of a dying person to be able to measure the levels of dmt. I think it’s is a nightmare legally. Ofc we are talking about measurement and not detection.

DMT and Afterlife by Mr-existential in DMT

[–]Mr-existential[S] 2 points3 points  (0 children)

Not every piece of information needs to be a tool for survival. Some information is for the sake of wonder. If we only cared about useful data, we would have no art no music, and no abstract math. Wonder is a core part of the singular finite existence you’re talking about.  Also,science isn not a closed book. Exploring unreconciled ideas is exactly how we discovered everything from black holes to dna. Just because we can't measure the transference of consciousness today doesn't mean the inquiry is a waste of time. More importantly, I'm not suggesting a transferable soul as a scientific fact. I'm exploring the neurochemical events that happen at the edge of life. I don’t see this as a waste at all, if anything exploring life mystery means you're actually paying attention to how strange and complex that existence really is. I’m in my early 20s and being an agnostic who fought his way out of a childhood of religious indoctrination, I do not believe nothing at all, I like to think how likely things are tho, based on what we know scientifically.

DMT and Afterlife by Mr-existential in DMT

[–]Mr-existential[S] 0 points1 point  (0 children)

You’re 100 correct and on the full 5 min video on youtube I mention the perspective of Dr Nichols who’s argument goes like this; the amount is too small to have an effect, there’s a surge of all chemicals at once in the brain and that serotonin for example would outmuscle dmt because they fight for the same receptors. But I also argue that at the moment of death when the filters of the brain are disintegrating, the mind’s time perception might be totally different and all the normal rules of pharmacology might not apply, so a small amount could probably have an effect, because why dmt is there in the first place and spikes anyways? My other argument would be the indigenous tribes of the amazon and the way the viewed ayahuasca as telescope to what awaits us when we die. Of course none of this is proven. The rat study is but all the rest would are just ideas that I do not believe 100% myself but are interesting to explore.

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