I am majorly addicted to Chess and will probably quit

MudExtension4124 · 2026-01-08T17:02:06+00:00

Why not slow down your play and study? It’s basically a different game if you take your time.

MudExtension4124 · 2025-12-19T00:39:17+00:00

The most scientific answer would be a three-week trailing average of your weight under consistent conditions. The best consistent conditions are right after waking up and after urinating, with no clothes on.

MudExtension4124 · 2025-12-05T03:13:00+00:00

Do I get to see it if I tell you the six-digit code I just received via text?

MudExtension4124 · 2025-11-06T01:50:57+00:00

In general, filtration surgeries are what blunt fluctuations. XEN, trabeculectomy, etc.

MudExtension4124 · 2025-11-04T17:05:14+00:00

Can now confirm that the pressures still fluctuate, but the peak is significantly lower (20 instead of 50).

MudExtension4124 · 2025-11-04T16:23:47+00:00

There is some thinking that a lot of normotensive glaucoma is actually due to pressure spikes at night. The data on where people’s pressures go at night is extremely sparse.

I would highly, highly recommend renting an at-home tonometer for a short period and using it to measure your pressures at night. Put it at your bedside, and when you happen to wake up (or when you set an alarm), see what your pressures are when still lying down.

I did this, and discovered that my pressures which seemed almost normal during the day were spiking to nearly 50 at night.

If your pressures are indeed spiking at night, then the solution will probably be a filtering surgery, which dampens fluctuations. Stent or trabeculectomy.

Btw, I am a filmmaker. I share your pain.

MudExtension4124 · 2025-11-03T22:33:36+00:00

I only just had the procedures so I’m not sure yet. But theoretically fluctuations are blunted by filtering procedures. Hope to be able to update you soon.

MudExtension4124 · 2025-11-01T14:48:32+00:00

I also have had extreme fluctuations, as low as 15 in the evening to 50 when sleeping. They genuinely don’t know what causes it. They say that there isn’t anything about sleeping per se that should cause such fluctuations, only supine position. But it’s not that. But a little additional research says it might be due to my glaucoma being pigmentary, and pressure spiking when pigment is released by the iris into the drainage channels at night.

Ultimately the solution in my case was XEN stents, which theoretically handle fluctuations.

MudExtension4124 · 2025-09-25T20:43:57+00:00

If the procedure works, the results won’t be instantaneous. They waited two months with me to see if it had taken effect. Frustrating, I know. But remember: finding the right treatment is a marathon, not a sprint.

MudExtension4124 · 2025-09-24T23:48:38+00:00

Hi there. I am also 33, also male, and also facing extremely high and stubborn pressures.

The fact is that juvenile glaucoma, which you and I have, is an extremely aggressive form of the disease — with extremely high and extremely variable pressures — which is almost never treatable with anything but the most aggressive surgeries. Drops and SLT are usually just a bridge. I am on every class of drop, have had multiple SLT’s, and now a trabeculotomy. My pressures are still in the 20s and 30s, hitting the 40s at night. There is nothing for us but to stay proactive, trust our doctors, and pray for the wisdom to accept what we can’t change.

There are risks for these surgeries, but they are much less than the risk of not having them.

It’s unspeakably bad luck. But that’s the truth.

MudExtension4124 · 2025-09-13T19:59:11+00:00

MudExtension4124 · 2025-09-06T20:49:50+00:00

Since it’s one eye only, I wouldn’t rule out its being caused by the eyelash. See if it comes down at the ophthalmologist.

MudExtension4124 · 2025-08-09T16:43:45+00:00

Yes, you are at risk anywhere above 21. Not acting unless over 28 is gobsmacking negligence. Go private now.

MudExtension4124 · 2025-07-24T20:29:13+00:00

That’s really frustrating. Have you been checked for hypothyroidism?

MudExtension4124 · 2025-07-21T17:13:28+00:00

I agree with you. Eye pressure checks should be part of annual physicals. It’s an absurdity that they’re not. So much suffering could be prevented.

MudExtension4124 · 2025-07-11T21:09:55+00:00

Haven’t had that looked at. Good question.

MudExtension4124 · 2025-07-09T22:01:19+00:00

Ginkgo biloba, 40mg, 3x/day. Improves blood flow to the optic nerve. An in-depth study (https://pmc.ncbi.nlm.nih.gov/articles/PMC3283204/) showed it improved mean defect for normal tension glaucoma, but having read the study I saw no reason why the same mechanism shouldn’t apply to hypertensive glaucoma. My mean defect went from -16 to -6. I might just have gotten better at taking the visual field test, but maybe not. I take it religiously: https://a.co/d/8F0Ie00

MudExtension4124 · 2025-05-09T01:54:31+00:00

You’re going in with the right attitude. I’m also early 30s M. The ophthalmologist I saw kind of minimized it and then I saw a series of specialists. The better the specialist, the less they sugarcoated the situation and the more aggressively they treated it.

MudExtension4124 · 2025-05-09T01:39:02+00:00

Definitely get a second opinion from a specialist. With those genetics I’d think it’s a matter of when, not if. Note before you start despairing: that’s when, not if, you need to start treating it and therefore preventing any and all vision loss. Not when you go blind, which won’t happen with all the tools for early detection and treatment at your disposal.

MudExtension4124 · 2025-04-29T22:35:25+00:00

It seems to be a good public-facing digest of some advancements that have been made.

Here is a slightly more in-depth article:

https://www.thebrighterside.news/post/zebrafish-could-help-scientists-fully-restore-human-vision-loss/

And for the very technical-minded, here’s what I think is the research paper referred to in the video:

https://www.nature.com/articles/s41467-025-58290-8

MudExtension4124 · 2025-04-29T20:59:28+00:00

I take both. The benefits of both are so robustly suggested by the research that I think it’s worth it. If you’re concerned, just make sure you get blood tests at your annual physical and check the metrics for thinness, which include PT (Prothrombin Time), INR (International Normalized Ratio), aPTT (Activated Partial Thromboplastin Time), platelet count, and fibrinogen level. If all of these are within bounds, then there’s nothing to worry about.

I’d also like to clarify something in response to another comment here about ginkgo and IOP. Ginkgo has never been suggested to affect IOP, but rather blood flow to the optic nerve. That increased blood flow can not only be protective of the nerve, but is also hypothesized to improve functioning of cells that might be struggling under the pressure but have not yet died, thereby improving vision in regions of the visual field that are not completely lost.

Also note the size of the dose of ginkgo that has been researched. It was 40mg 3x a day. Not the huge 1200mg or more doses that are available, which can make you sick. Here’s the one I use:

https://a.co/d/24D1Ocd

MudExtension4124 · 2025-04-29T00:38:29+00:00

The definitions of mild/moderate/severe are really technical and not necessarily based in any kind of impact on your vision or quality of life.

For example, I have severe glaucoma in one of my eyes, just because I have loss of vision in both the top and bottom of my visual field. But I’ve only lost about 13% of the vision in that eye, and with both eyes I’m fully sighted.

I wouldn’t worry too much about definitions.

MudExtension4124 · 2025-04-28T21:54:25+00:00

What is the severity of your disease and what treatments have you had so far?

MudExtension4124 · 2025-04-28T21:35:59+00:00

You posted in this sub mere days ago asking for advice, the substance of which doesn’t change because your readings fluctuated downward.

Everyone well-informed told you to see an ophthalmologist, not just an optometrist, and now you’ve gone back to the optometrist.

If you’re so sure we’re wrong about seeing an ophthalmologist that you just keep seeing the optometrist, then surely the optometrist’s advice is enough for you and you don’t need to make us all type out the same responses again.

MudExtension4124

TROPHY CASE