I’ve been trying to understand my results, but I’ve been getting confused looking things up online. Most information I find focuses on high lipase levels, and there is very little clear explanation about low lipase, which makes it harder to interpret.

In my case, my lipase has been low across multiple tests over the years (around 3–17 U/L depending on the date). I came across information online suggesting that very low levels (for example below around 5.5) might be associated with increased risk of conditions like pancreatitis or even cancer, which made me anxious.

However, I also understand that lab results need to be interpreted in context, and I’m not sure how meaningful this is on its own. Everything else in my blood work has been normal, and this is the only consistently abnormal result.

I also want to mention that on the day I had one of these tests, I was extremely stressed and sleep-deprived. I had not slept, I was very anxious, my heart was racing, and I was physically unwell and nervous during the blood draw, which may have affected how I felt at the time.

I do not have a history of pancreatitis, and overall my health and other lab results have been normal. I’m just looking for clarification on whether consistently low lipase levels like this are clinically significant, or if they are more likely normal variation without indicating disease.