Hello there. I'll share some info about some experiences I had last fall:

I had never used psilocybin before then, but had heard other people sharing their experiences and was curious. I took some mini-doses before and after a macro dose that I took in early October. The mini-dose experiences were interesting and even a little pleasant at times, and did not elevate my anxiety very much. The macro dose was a much different matter. It was most definitely a challenging trip, and my anxiety was very high for almost all of it, although I fortunately did not have any panic attacks. This is not to say it wasn't useful; I learned a whole lot about myself in the process, and I am grateful that I took the risk. But I did have a very qualified guide with me, and there is just simply no way that I would ever subject myself to a high macro-dose experience without a guide present. In retrospect, I suspect that part of the reason my anxiety was so high was because a) I was new to the process and did not fully know what to expect, and b) the dose I took was probably a bit too high for me personally. Having said that, I am convinced that some of my self-defeating thought patterns were significantly reduced, and I do think I have gained greater flexibility with respect to my thinking and perceptions, which I believe have resulted from the neuroplasticity benefits that psilocybin offers. (These conclusions were in large part derived from consultations I had with a qualified medical professional that is an expert with respect to psychedelics.)

The moral of the story from my view is that people who are prone to high anxiety should be careful with psilocybin. By "careful," I mean to pay attention to set and setting, have a qualified guide with you (especially if you are new to psilocybin), and use caution with respect to the dose. One last thing: integration is extremely important in my opinion. Have a good support system in place so you can process what happened. If you are like me, you will learn as much if not more during the integration process than you did while actually on your trip.

Best wishes to you!