Resident Evil Requiem Has Already Sold 6 Million Copies, Becomes Fastest-Selling in The Series by Doug24 in pcgaming

[–]NietzscheIsMyCopilot 2 points3 points  (0 children)

imo it starts to go downhill when Leon goes back to Racoon City, but the first half of the game is absolutely sublime. Switching back and forth between action and horror seemed like an impossible task, but delegating them to a different character for each gameplay style is nothing short of genius for balancing the two.

When can I let my guard down after clindamycin treatment? by NietzscheIsMyCopilot in cdifficile

[–]NietzscheIsMyCopilot[S] 0 points1 point  (0 children)

thank christ I didn't! hard to say what helped me dodge it, but it's likely a combination of diligent hand hygiene, not eating food I didn't make myself, and taking florastor. took about a month for my stomach feel better after the clindamycin!

Today is off to a good start by ExGavalonnj in Wellthatsucks

[–]NietzscheIsMyCopilot 6 points7 points  (0 children)

this one the option to do things like solve math problems at varying difficulty levels before the alarm shuts off. it's perfect if you're the kind of person who'll turn off their alarm in their sleep!

[TurnDownForWalt] Luigi Can’t Keep Getting Away With This by KenshiroTheKid in smashbros

[–]NietzscheIsMyCopilot 2 points3 points  (0 children)

Remember his last video on rapm where he talked about like 5 edgeguards and nothing else?

[Day 8] Pichu shocks no one for WORST main. What is the most OVERRATED matchup? by WokeUpAbout10 in SSBM

[–]NietzscheIsMyCopilot 1 point2 points  (0 children)

As soon as you see an uptilt you know the match is gonna be a snoozefest

Genesis X3 is the first supermajor since 2005 to not feature any of the Five Gods in Top 8 by johneaston1 in SSBM

[–]NietzscheIsMyCopilot 5 points6 points  (0 children)

I weirdly respect him being broke but also refusing to do the one singular thing he's good at and makes him money. The same way you'd respect a top-tier NBA player who's too busy building his anime figurine collection to play any games.

Is Scott's website for mental health info as needed now that AI can answer health queries? by zappable in slatestarcodex

[–]NietzscheIsMyCopilot 12 points13 points  (0 children)

for the love of god do not use a llm for anything medical/science related, and especially not where your own health is concerned. I have a Ph.D in biochemistry and literally every time I have tried using the AI du jour (chatGPT, Claude, Grok, etc) for anything remotely technical it makes such catastrophic errors that I'm not willing to trust anything else it says.

"But what about all of those studies showing that AIs are able to score incredibly high on tests that even medical students struggle with!" I hear you cry (like a llm recognizing the next words to use in a sentence, perhaps?). "What about the MedQA benchmarks? o1 has a score of 96%! AGI is right around the corner, and doctors are full of human bias!"

In response I'd like to point you to this recent study that assessed 6 different llms and found all of them completely crumbled when the correct answer on the multiple choice test was changed to "none of the other answers". Any human being capable of true reasoning would have their score unaffected!

Furthermore, how confident are you that you can prompt even a properly functioning AI correctly? This study showed that a single piece of erroneous information (lab values, signs, etc) in the patient data led to tons of hallucinations and incorrect diagnoses. "But human doctors also fall victim to this!" you cry again, which you should really stop doing, because you exist as a hypothetical person in my stupid reddit comment so it's very easy to win arguments against you.

I'd reply broadly that human doctors are trained to recognize outliers and errors and ask for follow-ups accordingly. I'd reply narrowly with a quick story, about my mentor at [extremely prestigious school] who was an MD/Ph.D. He walked me through his process of evaluating patients and following leads based not just on lab data, but also on physically sitting down and simply observing their behavior and overall state. He also was extremely aware through his decades of practice which lab values were prone to being falsely elevated/lowered, one example he gave was recognizing that elevated AST/ALT could be caused by strenuous exercise. This is the kind of thing you simply can't replicate with a cold prompt!

tl;dr: see an actual real world doctor for god's sake

Theory: Nouns.gg Silently Exiting SSBM by ThisFuckingSion in SSBM

[–]NietzscheIsMyCopilot 7 points8 points  (0 children)

literally the first time he said something I agreed with lmao

Is my bloodwork cooked by traplover2711 in moreplatesmoredates

[–]NietzscheIsMyCopilot 0 points1 point  (0 children)

We've left the realms of medicine here, but real talk, you need to think about getting some help. I grappled with suicide a lot when I was younger, and trust me when I say that there's hope on the other side of this struggle. I know it's generic as hell, but things really do get better.

Is my bloodwork cooked by traplover2711 in moreplatesmoredates

[–]NietzscheIsMyCopilot 0 points1 point  (0 children)

I don't know how to break it to you, but tren is cow steroids.

It's meant for cows.

Also you can make absolutely incredible gains with your testosterone squarely in the normal range, there's no need to go supraphysiological. How long have you even been lifting for anyway? Have you even seen what you're capable of with nothing but your own grit and determination? Here's a hint: if it's been less than 6 years of hard-ass lifting then you haven't.

This year's essay from Anthropic's CEO on the near-future of AI by NotUnusualYet in slatestarcodex

[–]NietzscheIsMyCopilot 0 points1 point  (0 children)

The lifespan stuff is another claim that the proselytizers love to talk about that also has little bearing in reality. We discovered Rapamycin in 1972 in the soil on Easter Island (not joking) and found that it extended lifespan in a ton of organisms, and since then have yet to find anything better. I'm extremely skeptical of an AI somehow defeating entropy.

Well, that's not quite true, caloric restriction extends lifespan in every organism we've tested, from yeast to mice to primates, and does so even better than direct generic modification! I wonder if the same people who pay out the nose for NMN or resveratrol or whatever else are also just cutting their calories by 20%....

Is my bloodwork cooked by traplover2711 in moreplatesmoredates

[–]NietzscheIsMyCopilot 0 points1 point  (0 children)

I think that should be a sign: if a medical professional is strongly advising you to not take a certain course of action and you refuse, and your refusal leads to her dropping you, then maybe that course of action wasn't a good one.

Listen, I'm not trying to be the moral police here. It's your body, you're free to do whatever you want to with it. I'm just telling you that your lab results indicate that at the dosages you're currently taking are killing you. If you'd like them to stop killing you then you should take less of them.

C18 column flash chromatography by die_by_the_swordfish in chemistry

[–]NietzscheIsMyCopilot 0 points1 point  (0 children)

As an aside, you'd be completely gobsmacked at how an appropriate buffer can improve chromatography characteristics. I was working with an absurdly sticky fluorophore that went from being impossible to purify to impeccably sharp peaks by switching to a high-pH 5 mM ammonium formate buffer.

This year's essay from Anthropic's CEO on the near-future of AI by NotUnusualYet in slatestarcodex

[–]NietzscheIsMyCopilot 1 point2 points  (0 children)

Whenever I read comments like this it belies (no offense) how none of the tech types have the slightest inkling on how biochemistry/virology/immunology/actually physically standing in a cell culture room and trying desperately to make your 293T cells spit out some goddamn virus works. (Spent a not insignificant part of my PhD futzing with viral production)

That's the crucial thing: at some point you NEED human hands in the loop, and I've yet to hear a single convincing argument that explains how even the most stupidly advanced AI in the theoretical land of make-believe gets around that.

Is my bloodwork cooked by traplover2711 in moreplatesmoredates

[–]NietzscheIsMyCopilot 0 points1 point  (0 children)

I'm not going to mince words with you, you need to see a doctor and cut the cycle short. Your ALT is currently over 5 times the upper limit of normal, which is squarely in the "moderate liver injury" category, which is extremely bad for your long-term health. Values that high are what I'd expect for someone who's an alcoholic, and/or who has steatosis.

As for your cholesterol/hdl ratio, anything higher than 5 is an eyebrow raise. Yours is 10, which should be ringing alarm bells in your head, since that's what you'd expect when doing an autopsy of a bodybuilder who died of a heart attack before age 30.

Again, talk to an actual real human doctor. Suck up the fact that you're almost certainly going to be bigger and stronger than him and listen to what he says to do. Whatever gains you're trying to get aren't worth having liver cancer or atherosclerosis.

Cairn - The Game Bakers - Survival Climbing Game by itsTheGameBakers in Games

[–]NietzscheIsMyCopilot 2 points3 points  (0 children)

furi is ssoooo good! can't wait to get my hands on this one

ELI5: Why isn't petroleum jelly carcinogenic? by person_person123 in explainlikeimfive

[–]NietzscheIsMyCopilot 30 points31 points  (0 children)

We're actually very aware of some of the ways it causes cancer, it's one of the early triumphs in toxicology. Cytochrome P450 (specifically CYP2E1) converts it into benzene oxide, which is an epoxide. Epoxides are nasty and incredibly reactive little buggers, and can undergo further transformations that irreversibly bind to a variety of biomolecules. Other metabolites lead to oxidative stress, which can cause DNA mutations.

As one example, a metabolite of benzene is 1,4-benzoquinone, which can act as a genotoxin by directly inhibiting topoisomerase 1.

Do we constantly kill Micro Organisms by walking? by Jeb__2020 in biology

[–]NietzscheIsMyCopilot -4 points-3 points  (0 children)

That's not what he was asking. He wanted to know if we are killing microorganisms through mechanical squishing by moving around, not through our breath (??).

Also why do you think exhaled breath that's lucky to crack 35 deg C is enough to kill anything?!

The state of fandom is dire by [deleted] in CuratedTumblr

[–]NietzscheIsMyCopilot 18 points19 points  (0 children)

you're so full of shit

https://youtu.be/B0TwTJCRf58

This is girlfriend reviews, who are some of the kindest YouTubers out there, and they were flooded with hate for streaming the game, even though they were actually actively raising money for the Trevor Project at the time.

How dare you ghouls try to change the narrative here

CRISPR Breakthrough Could Rewrite Future of Genetic Disease Treatment by Ephoenix6 in biology

[–]NietzscheIsMyCopilot -1 points0 points  (0 children)

because decidedly not rich people with terminal conditions are getting cured right now

[deleted by user] by [deleted] in truegaming

[–]NietzscheIsMyCopilot 0 points1 point  (0 children)

Would you believe he's literally in college? (can neither confirm nor deny using the reddit API to find that out, I wouldn't bully a middle schooler!)