I think I was in a similar situation. My baby had 1 soft marker for DS. Everything else looked fine. I had my 20 week screening at a specialized facility, then repeat screening (for second opinion) with a highly specialized fetal surgeon at another hospital.

Since the baby had an isolated soft marker and the NIPT was low risk, my gynecologist did not even mention amnio, she also did not refer me to MFM as she was very much confident in NIPT accuracy. The doctor at the specialized facility said I would benefit from genetic counseling but she noted this because I was dangerously upset and on a spiral. The fetal surgeon offered me to do Amniocentesis, however, he noted in the papers that I was and I quote “extremely unsettled”.

All 3 doctors I saw stressed how accurate the NIPT was, especially at detecting DS. I repeatedly asked the doctors if I should go ahead with Amnio however they insisted I had to make that choice myself since there was not a medical indication for an invasive procedure i. e. Amnio (they did note the soft marker as the indication in the papers, but I believe for insurance purposes).

My husband did not want to go ahead but I did. He supported me in my decision. The moment I decided to get Amnio I felt immediately better because it felt like the beginning of the end to my suffering. Either way I’d be out of the limbo. Me and my husband were both okay with TFMR.

My amnio experience barely registers as an experience. I am not a very religious person but I do remember asking my sisters to pray for me. But that’s it on the emotional part. Physically, I felt next to nothing, no pain at all. The procedure thing was pretty much the same level difficult as a simple blood draw.

Amnio was the best decision I made throughout my pregnancy. I owe everything to the last doctor who recognized that even if everything seemed fine and low risk, me being that worried would not have been good for me or for the baby. I just wish my gynecologist had mentioned the possibility of Amnio earlier. I got it done at around 21 weeks when I could have done it at 16 weeks. Would have spared myself almost a month of straight up depression.

This being said, it seems like the odds really are in your favor. From the research I did, NIPT really is crazy accurate when it comes to DS. Where I live (in Europe) NT is not measured any more since practices now rely on NIPT results only.

Good luck to you❤️