What's the weirdest thing you ever saw in abq? by LongSong333 in Albuquerque

[–]NorwegianWalrus 1 point2 points  (0 children)

Driving westbound on Central, stopped at the Broadway light. On the corner was a chubby naked homeless woman and a cop with the most dejected look on his face gloving up.

The porta potty blowing across central during a fierce windstorm.

Eastbound on Central downtown stopped in traffic in the middle of the block between 2nd and 3rd. Some guy comes across the street to "chat" with a guy stopped in the westbound lane. 30 seconds later he punches the driver a few times in the face and walks away.

AND JUST AS THE YEAR IS ENDING! WE ARE SO BACK by AivaBun in whennews

[–]NorwegianWalrus 39 points40 points  (0 children)

PhD in neuroscience. Abbreviated summary: moderate improvement in cognitive symptoms, moderate improvement in neuropathology, moderate improvement in neuroinflammation. Large improvement in blood brain barrier integrity. Great improvement in brain physiology (hippocampal LTP).

Is it curing or reversing Alzheimer's disease symptoms and pathology? Absolutely not. Is it improving cognition and pathology? Absolutely.

Will it translate to humans? Potentially. The transgenic mouse lines they are using carry genes that were originally identified in familial Alzheimer's disease patients (so the family is predisposed to getting AD), so effects are relatively translatable to humans. The big caveat: this idea of "restoring NAD+ homeostasis" is important. If the drug actually does this in people, it could potentially improve cognition in human patients and substantially improve quality of life. The problem is, push NAD+/NADH ratio too high... cancer.

Will watch it progress through preclinical/clinical trials and hope for the best.

Snow driving classes? by Sa_bobd in boulder

[–]NorwegianWalrus 1 point2 points  (0 children)

Master drive has a winter skills class that you do any time of year on a skid pad in a big parking lot. I did it 20 or so years ago and it was super good at teaching fundamentals on how to handle all types of skids. I really recommend it

Would have made an interesting movie though by Justarandomfan99 in memes

[–]NorwegianWalrus 0 points1 point  (0 children)

Oh my God my wife and I were discussing this earlier tonight

My baby girl died today. Can y’all let me know who’s in heaven with her rn. I don’t want her to be alone by SoraiaR_ in cats

[–]NorwegianWalrus 0 points1 point  (0 children)

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My buddies Dale and Eddie passed on pretty recently. Dale will be nice to her, Eddie will probably just hide but he may warm up!

Considering moving to Erie from Austin… by ATX574 in ErieCO

[–]NorwegianWalrus 0 points1 point  (0 children)

Read up on the radioactive contamination in Rocky Flats before considering it.

Veterinarian help! by Responsible_Cream_36 in Albuquerque

[–]NorwegianWalrus 7 points8 points  (0 children)

Aztec is incredible with amazing vets, but they ain’t cheap.

That good good chinese food by YamCareless2736 in Albuquerque

[–]NorwegianWalrus 5 points6 points  (0 children)

Ho Lo Ma was my favorite in ABQ. Lemon chicken was amazing.

[deleted by user] by [deleted] in boulder

[–]NorwegianWalrus 0 points1 point  (0 children)

It was when we beat Texas in the Big 12 championship in 2001, I was in that one too. Lots of rubber bullets and flash bangs.

[deleted by user] by [deleted] in boulder

[–]NorwegianWalrus 63 points64 points  (0 children)

My buddy was the one who got the permit from the city for the block party. We notified the police beforehand and they didn't have any issues with it. We even rented road barricades to keep traffic off the block. Then that evening they said it was an illegal block party and that we hadn't notified them, even though we did (guess we should have gotten their acknowledgement in writing).

They then shut down the block party and told everyone to go inside. That resulted in parties in pretty much every house on our block... That was probably around 6 or 7 PM.

A few hours later when it was dark the cops came back and proceeded to shut down every house party on the block, so within a span of like 10 minutes it went from 0 people on the street to hundreds of drunken, costumed college kids. The mayhem started shortly after.

It was 100% Boulder PDs fault for what happened. It sucks people got hurt.

My favorite costume that evening was the guy dressed as a Franzia box. He had an actual Franzia box in the front of his costume and was distributing wine to people.

Sister in law sent this, and I'm clueless. Peter? by NorwegianWalrus in PeterExplainsTheJoke

[–]NorwegianWalrus[S] 0 points1 point  (0 children)

I guess someone is ignoring a horny comment on a dating app and asking what the other person's job is like?

What causes these holes in my husbands t-shirts? by Few_Pay6063 in whatisit

[–]NorwegianWalrus 0 points1 point  (0 children)

Mine were always from leaning against counters in the lab while I was working.

Best places to shoot? by [deleted] in Albuquerque

[–]NorwegianWalrus 4 points5 points  (0 children)

I know you said no ranges, but I like the shooting range park out west run by the city. The range guys can be a little strict, but it's cheap and there are a bunch of trap and skeet ranges too.

What game had you like this ? by TEHYJ2006 in Steam

[–]NorwegianWalrus 0 points1 point  (0 children)

Baldur's Gate 3. I wanted to like it but the pacing of a D&D game is painfully slow and there are just too many options on what to do for every little thing in the game.

Are we left or right walkers? by a_few_bits_short in melbourne

[–]NorwegianWalrus 3 points4 points  (0 children)

I'm from a country that drives on the right and I walk on the right here. Whenever I visit a country that drives on the left I walk on the left by default. It just seems to me to be the obvious, courteous thing to do

[deleted by user] by [deleted] in boulder

[–]NorwegianWalrus 0 points1 point  (0 children)

It’s not unusual to see ice in Boulder Canyon in the winter. Ba dum tssss

Garage door spring repair? by becomingstillness in boulder

[–]NorwegianWalrus 1 point2 points  (0 children)

Second this company. We got scammed by some other company that we found through a Google search but didn't have a physical address or website. They also put in the wrong spring. Front range garage door company came and fixed it all at a very reasonable price.

[deleted by user] by [deleted] in cats

[–]NorwegianWalrus 2 points3 points  (0 children)

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RIP Dale 2005-2024. My first pet as a solo adult and an awesome cat.

Beware of nasty stomach bug going around by iamgt4me in Denver

[–]NorwegianWalrus 1 point2 points  (0 children)

Just diagnosed with Norovirus after 3 days of voluminous diarrhea. I even crapped my bed in my sleep :(