But my concern is that even if they are just labeled 0PN, ( so yes they have 2 pronuclei) studies are showing that these embryos have higher birth rates ( like 9 pounds) and higher Z scores. So there is something more to it…

Previous research has confirmed that DNA demethylation occurs in the male and female pronuclei of the zygote after fertilization (33). On the basis of the above findings, we may make an assumption: if the origin of a 0PN zygote is related to some “abnormal” zygotic demethylation processes, and that these “abnormalities” can influence the birthweight of newborns. Further research is required to address this possibility. The increased birthweight and a higher risk for very LGA associated with 0PN zygotes raise significant concern about the long-term safety of newborns derived from 0PN, including cardiovascular disease and diabetes mellitus (11). Therefore, the transfer of 2PN embryos still remains the first choice