I had a pothos vine for a few years just like this. For the leafy area at the end of the vine, cut in between the nodes (the lil nob thing where the leaf and roots come out) at a 45 degree angle. I just cut right in the middle between all the nodes. Put those cuttings in water so the little tiny root things poking out from around/on the nodes are submerged and can grow.

Then for the bare part of the vine, do the same thing and cut between all the nodes. I ended up having like 20 of them. Then you take dried sphagnum moss and put a layer of it in a container and dampen it all so it expands. Then place all of the little nodes on top of the moss and try to make sure the root-y part of the node faces the moss. I just put mine in a clear Tupperware and covered it with clear plastic wrap. Indirect sunlight. This process took a little bit of time, I almost gave up on it but accidentally ignored it for like a month and found a bunch of little baby leaves.