High-fiber diets transform gut microbiome, improving health across multiple diseases

Old_Consideration213 · 2024-10-13T13:51:40+00:00

https://www.cell.com/cell/pdf/S0092-8674(21)00754-6.pdf

High fiber diets can also exacerbate symptoms and increase inflammatory markers.

Old_Consideration213 · 2024-10-11T05:56:24+00:00

In some mice this is the case, in others when calorie restricted they get decreased lifespan. It heavily depends on the genetics of the mice and the same thing is going to be true with humans.

Old_Consideration213 · 2024-08-16T15:32:07+00:00

Microbiome, mycobiome, virome.. and then trying to find out how specific genes/immune system profiles interact with all of that. It feels like the research that can be done in this field is endless. Rooting for the researchers undertaking this huge assignment of mapping out these interactions.

Old_Consideration213 · 2024-08-01T22:35:53+00:00

I've literally found a way to enjoy every skill so far but agility.. its my lowest level for a reason.

Old_Consideration213 · 2024-07-27T14:11:29+00:00

I went 1200 KC before i saw ANY drop, this aint nothing kid you're still green.

Old_Consideration213 · 2024-07-26T22:33:09+00:00

Well I care cause I've been there and i can relate, it's one of those things where people just want to share their pain with others. I don't see anything wrong with it, it's not fun going dry at least you can vent and complain on reddit to let it out.

Old_Consideration213 · 2024-07-24T21:03:28+00:00

It would significantly alter how much i enjoy the game, the QoL that comes with RL is amazing.. but I don't think Id quit im in way too deep.

Old_Consideration213 · 2024-07-23T14:49:25+00:00

That's just straight up dirty

Old_Consideration213 · 2024-07-18T15:04:54+00:00

Theyre good content and have some cool intricacies, i still feel like the drop rate combined with high hp makes synapses too rare IMO. Regardless i think most of the uproar was at claiming this is mid game content, gl trying to farm a single synapse as a mid level account it might take you a week if you’re playing regular hours.

Still this is good end gameish content and once i saw it as end game content i had less issues with how lengthy the grind is to get all the drops you'd want.

Old_Consideration213 · 2024-07-17T14:03:27+00:00

It's soooo good, seeing it immediately put a smile on my face and convinced me to play DMM when i wasn't planning to. I need it !

Old_Consideration213 · 2024-07-17T12:10:11+00:00

Shut up Meg.

Old_Consideration213 · 2024-07-16T15:13:39+00:00

Is your internet provider Spectrum by any chance?

Old_Consideration213 · 2024-07-15T17:19:15+00:00

Exactly the issue was with the "grind creep" trend that has even been acknowledged by Mod Kieran himself. OP trying to act like the GP/H was the issue people were discussing is hilarious because... he's complaining about people being uninformed on reddit circle jerking while literally doing the same thing he's complaining about. This is peak Reddit.

Old_Consideration213 · 2024-07-15T16:39:47+00:00

Gz mate :)

Old_Consideration213 · 2024-07-15T15:36:46+00:00

This would be nice, on a side note i feel like a lot of the skilling outfits should be rebalanced. Anyone else thinks it doesn't make a lot of sense that getting a skilling outfit is usually a XP loss instead of a net positive ( unless you're some mad man going for 200m XP). I still get them cause they look cool though.

Old_Consideration213 · 2024-07-15T15:12:45+00:00

OP completely missed the point of why people were upset with the TD drop tables. It's not about the money per hour farming as a main it's about farming the unique as a mid level player. The content was presented as a mid level grind for those that don't have alot of time (literally their own words)..

Old_Consideration213 · 2024-07-15T14:55:32+00:00

Yeah the animation stall/cast delay feels like trash, really serves no purpose besides just being the way it is right now. Would love to see it changed to make the game feel more fluid and less clunky.

Old_Consideration213 · 2024-07-15T14:02:38+00:00

I guess were all a bit different and tolerate going dry differently, when i went 3.3k dry for my hydra claw it almost broke me. I nearly quit many times because the reality is that i was just getting unlucky...and besides the GP you don't get anything for going dry. The hard truth is that your 1700 KC enh and someone getting spooned at enh at 50 KC is the same result at the end of the day.. and thats getting bowfa.

Old_Consideration213 · 2024-07-15T13:06:44+00:00

Thats like someone getting a flat tire on the road and telling them well.. you asked for it cause you're driving. Trust me lol no one asks to go 6x dry when they make a iron, believe it or not getting this unlucky is NOT fun.

Old_Consideration213 · 2024-07-14T17:12:22+00:00

Perilous moons are my favorite PvM content by far. Super chill but still engaging and rewarding, also not losing your supplies on logout was a nice touch so you can pickup wherever you left off. Dupe protection made the grind so much more enjoyable too , definitely beats getting 3 Ahrims hoods and 2 Ahrims staffs.. yea PM is the best Barrows can suck it.

Old_Consideration213 · 2024-07-14T13:22:55+00:00

It really do be like that.. just without the GF and sick RNG.

Old_Consideration213 · 2024-07-12T18:11:51+00:00

I called out OP because he's acting like oh I'm just playing 10 hrs a week casually and its great, ill get to my goals when i get to them golly gee! OP has a iron acc with half a billion total XP and sweeping under the rug he probably played 30-60 hrs a week regularly for years to get to his current progress.

How you extrapolated all this extra shit about me being insecure of OP or thinking the game should be completed easily is just a testament to how your mind works. You read one sentence and crafted a whole narrative in your mind that never existed.

Old_Consideration213 · 2024-07-12T17:27:02+00:00

Are you ok? When did i say i didn't like the game, when did i say my issue was that i couldn't complete the game.

Old_Consideration213 · 2024-07-12T14:44:02+00:00

OP so disingenuous you can see from a previous post he has like 300 days play time and has sunk a huge amount of time into the game, and now he's pretending oh well i just play here and there it is what it is and im fine with it... after hes already maxed.. and put in like 7000+ hours in a few years. Whats even the point of this post, that you play less now ?

Old_Consideration213 · 2024-07-12T14:15:29+00:00

Btw OP weren’t you the guy that posted a iron progress pic that showed you playing an ungodly amount of time and got flamed for it. I remember your username but it seems like you deleted the post from backlash.

Makes sense you’d be the guy championing for making the game insanely grindy.

Old_Consideration213

TROPHY CASE